From the Guidelines
Benign facial flushing can be effectively managed with topical treatments such as microencapsulated benzoyl peroxide 5% (E-BPO 5%), which has been recently approved by the US Food and Drug Administration (FDA) in 2022 1. Treatment options for benign facial flushing include both lifestyle modifications and medical interventions. Avoiding triggers like spicy foods, alcohol, hot beverages, and extreme temperatures can significantly reduce episodes.
- Topical treatments such as E-BPO 5% can be used to effectively deliver benzoyl peroxide to the skin, reducing the risk of skin irritation and increasing therapeutic response 1.
- Other topical treatments like minocycline foam, which was FDA approved for rosacea in 2020, may also be considered.
- Oral medications and laser therapy options may be used for more severe cases, but E-BPO 5% is a promising new treatment option that can be tailored to the specific needs of each patient 1. Key considerations in managing benign facial flushing include:
- Identifying and avoiding triggers
- Using gentle skin care products
- Adhering to pharmacologic treatment
- Tailoring treatment to the individual's specific signs and symptoms 1.
From the Research
Treatment Options for Benign Facial Flushing
Benign facial flushing can be treated with various medications and therapies. The treatment options include:
- Beta-blockers, such as propranolol, which have been shown to suppress flushing reactions in some patients, particularly when associated with anxiety 2
- Clonidine, which is currently the only drug available for the treatment of flushing 3
- Topical and systemic therapies, such as metronidazole 1% cream and azelaic acid 20% cream, which have been reported to reduce the severity score of erythema 3
- Venlafaxine, which has been shown to effectively improve flushing that may be related to anxiety 4
Lifestyle Changes and Other Considerations
In addition to medical treatments, lifestyle changes and other considerations may also be helpful in managing benign facial flushing. These include:
- Avoiding triggers that can cause flushing, such as spicy foods, hot drinks, and stress
- Using over-the-counter medications and other strategies to reduce the visible effects of flushing, although this may not be recommended as it can lead to increased alcohol consumption 5
- Addressing underlying conditions, such as rosacea, that may be contributing to the flushing 3, 6
Important Considerations for Diagnosis and Treatment
It is essential to note that flushing can be a symptom of various conditions, including serious diseases such as carcinoid syndrome, pheochromocytoma, and mastocytosis 6. Therefore, a thorough diagnosis and workup are necessary to determine the underlying cause of the flushing and to develop an effective treatment plan.