Differential Diagnosis for Nodules on Finger Joints
Single Most Likely Diagnosis
- Rheumatoid Arthritis (RA): This is a common autoimmune disorder that often presents with nodules on the finger joints, among other symptoms like joint pain, swelling, and morning stiffness. The presence of nodules, particularly on the extensor surfaces of the fingers, is a hallmark of RA.
Other Likely Diagnoses
- Osteoarthritis (OA): While OA is more commonly associated with joint pain and degeneration, it can also present with Heberden's and Bouchard's nodes, which are bony enlargements of the distal and proximal interphalangeal joints, respectively.
- Psoriatic Arthritis (PsA): This condition can cause a variety of skin and joint manifestations, including nodules on the fingers, especially in patients with a history of psoriasis.
- Gout: Gouty tophi, which are deposits of uric acid crystals, can form nodules on the fingers, especially in patients with a history of gouty arthritis.
Do Not Miss Diagnoses
- Sarcoidosis: This systemic disease can cause granulomatous inflammation that may lead to nodules on the fingers, among other symptoms. Missing this diagnosis could lead to significant morbidity due to its potential to affect multiple organ systems.
- Lupus: Systemic lupus erythematosus (SLE) can cause a wide range of symptoms, including joint pain and nodules. It's crucial not to miss this diagnosis due to its potential for serious complications.
- Infectious Arthritis: Certain infections, such as tuberculosis or fungal infections, can cause nodules on the fingers. These conditions require prompt diagnosis and treatment to prevent serious complications.
Rare Diagnoses
- Multicentric Reticulohistiocytosis: A rare condition characterized by the formation of nodules on the skin and joints, including the fingers, due to the proliferation of histiocytes.
- Relapsing Polychondritis: An autoimmune disorder that can cause inflammation and destruction of cartilaginous structures, including the formation of nodules on the ears, nose, and joints.
- Sjögren's Syndrome: An autoimmune disorder that primarily affects the exocrine glands, but can also cause joint pain and nodules, among other systemic symptoms.