From the FDA Drug Label
Each gram of Hydrocortisone 1% – Iodoquinol 1% Cream contains 10 mg of hydrocortisone and 10 mg of iodoquinol in a greaseless base of cetyl alcohol, glyceryl monostearate SE, isopropyl myristate, lanolin alcohol, mineral oil, polyoxyl 40 stearate, polysorbate 20, polysorbate 60, propylene glycol, purified water, sorbic acid, and sorbitan monostearate. Hydrocortisone is an anti-inflammatory and antipruritic agent, while iodoquinol is an antifungal and antibacterial agent.
The treatment for intertrigo using topical hydrocortisone and iodoquinol involves applying Hydrocortisone 1% – Iodoquinol 1% Cream.
- Key ingredients: hydrocortisone (anti-inflammatory and antipruritic) and iodoquinol (antifungal and antibacterial).
- Application: apply the cream to the affected area.
- Precautions:
- For external use only.
- Keep away from eyes.
- Keep out of reach of children.
- If irritation develops, discontinue use.
- Potential risks:
- Staining of skin, hair, and fabrics may occur.
- Increased systemic absorption of corticosteroid if extensive areas are treated or occlusive technique is used.
- Interference with thyroid function tests.
- Special considerations:
From the Research
Intertrigo can be effectively treated with a combination of topical hydrocortisone and iodoquinol, as this combination addresses both the inflammatory and infectious components of the condition. For treatment, apply a thin layer of hydrocortisone 1% with iodoquinol 1% cream or ointment to the affected skin folds twice daily for 7-14 days, as recommended by various studies 2, 3. Before application, gently clean and thoroughly dry the area to prevent further irritation and promote healing. The medication should be applied sparingly, covering only the affected areas and a small margin of surrounding healthy skin. Improvement is typically seen within a few days, but complete the full course of treatment to prevent recurrence, as suggested by a study published in 2014 3. Hydrocortisone works by reducing inflammation, redness, and itching, while iodoquinol provides antifungal and antibacterial properties to address the microbial overgrowth common in intertrigo. This combination is particularly effective because intertrigo often involves both inflammation and secondary infection, as noted in a study from 2006 4. To prevent recurrence, keep skin folds clean and dry, wear loose-fitting clothing, and consider using absorbent powders in problem areas, as advised by a study from 2005 2. If symptoms worsen or don't improve after 7 days, discontinue use and consult a healthcare provider as a different treatment approach may be needed, such as the use of isoconazole nitrate and diflucortolone valerate combination therapy, which has been shown to provide rapid relief of intertrigo-associated pruritus due to Candida albicans 5. Additionally, maintaining good hygiene and avoiding irritants can help prevent intertrigo, as suggested by a study from 2007 6. Overall, the treatment of intertrigo requires a comprehensive approach that addresses both the underlying causes and the symptoms of the condition.