From the FDA Drug Label
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From the Research
The appropriate workup for a localized muscle spasm should begin with a thorough history and physical examination to identify potential causes, followed by initial management with rest, ice, and heat, and consideration of over-the-counter analgesics and muscle relaxants for severe cases, as supported by studies such as 1 and 2. The initial assessment should include evaluating the location, duration, severity, and any precipitating factors of the spasm.
- Rest, ice for acute spasms (15-20 minutes every 2-3 hours), and heat for chronic spasms are recommended as initial management strategies.
- Over-the-counter analgesics such as acetaminophen (500-1000mg every 6 hours, maximum 4g daily) or NSAIDs like ibuprofen (400-600mg every 6-8 hours with food) can help reduce pain and inflammation, as discussed in 3.
- Muscle relaxants such as cyclobenzaprine (5-10mg three times daily) or baclofen (5-20mg three times daily) may be prescribed for short-term use (7-10 days) in severe cases, with cyclobenzaprine showing efficacy in improving muscle spasm and reducing local pain and tenderness, as shown in 1. Physical therapy focusing on gentle stretching and strengthening exercises is beneficial for recovery and prevention, and can be considered in conjunction with other management strategies. If spasms persist beyond 1-2 weeks, recur frequently, or are accompanied by neurological symptoms, further diagnostic testing may be warranted, including:
- Blood tests to check electrolytes, calcium, and magnesium levels
- Imaging studies like X-rays or MRI to rule out structural abnormalities, as suggested in 2. Muscle spasms often result from overuse, dehydration, electrolyte imbalances, or underlying musculoskeletal conditions, so addressing these root causes is essential for effective treatment and prevention, as noted in 3.