Should oral corticosteroids be tried for lumbar strain if Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and muscle relaxants are not effective?

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Last updated: February 26, 2025View editorial policy

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From the Guidelines

Oral corticosteroids should not be tried for lumbar strain if Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and muscle relaxants are not effective, as they have not been shown to be more effective than placebo. The use of systemic corticosteroids for low back pain with or without sciatica is not recommended due to lack of evidence supporting their effectiveness 1. Instead, consideration should be given to non-pharmacologic therapies with proven benefits, such as spinal manipulation for acute low back pain or intensive interdisciplinary rehabilitation for chronic or subacute low back pain.

Some key points to consider when managing lumbar strain include:

  • The limited evidence supporting the use of oral corticosteroids for acute low back pain, with most studies showing minimal to no benefit 1
  • The potential side effects associated with steroid use, including mood changes, elevated blood sugar, increased infection risk, and fluid retention
  • The importance of maintaining mobility and avoiding bed rest, as this can help promote natural resolution of inflammation and improve outcomes
  • The need for further evaluation if pain persists beyond 4-6 weeks to rule out other underlying causes of back pain

In terms of alternative treatment approaches, options such as physical therapy, gentle stretching exercises, application of heat or cold, and gradual return to normal activities as tolerated may be beneficial for patients with lumbar strain who do not respond to NSAIDs and muscle relaxants. The focus should be on promoting natural recovery and maintaining mobility, rather than relying on oral corticosteroids with limited evidence of effectiveness.

From the Research

Treatment of Lumbar Strain

  • The provided studies do not directly address the use of oral corticosteroids for lumbar strain when NSAIDs and muscle relaxants are not effective 2, 3, 4, 5, 6.
  • However, the studies suggest that NSAIDs and muscle relaxants are commonly used to treat low back pain, including lumbar strain 3, 4, 5, 6.
  • In cases where NSAIDs and muscle relaxants are not effective, other treatment options may be considered, such as physical therapy, heat therapy, and spinal manipulative therapy 3, 4.
  • One study mentions the use of corticosteroid injections for sacroiliac sprain syndrome, but this is not directly related to lumbar strain 2.
  • There is limited evidence on the use of oral corticosteroids for lumbar strain, and more research is needed to determine their effectiveness in this context.

Current Treatment Guidelines

  • The current treatment guidelines for low back pain, including lumbar strain, recommend the use of NSAIDs and muscle relaxants as first-line treatments 3, 4, 5.
  • If these treatments are not effective, other options may be considered, such as physical therapy, heat therapy, and spinal manipulative therapy 3, 4.
  • The use of oral corticosteroids is not typically recommended as a first-line treatment for lumbar strain, but may be considered in certain cases where other treatments have failed 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Sacroiliac sprain: an overlooked cause of back pain.

American family physician, 1992

Research

Treatment of low back pain: myths and facts.

Schmerz (Berlin, Germany), 2001

Research

Evaluation and treatment of acute low back pain.

American family physician, 2007

Research

A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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