Differential Diagnosis for Lesion on Penis
- Single most likely diagnosis
- Genital herpes: This is a common sexually transmitted infection that can cause painful lesions on the penis. The high prevalence of herpes simplex virus among sexually active individuals makes this a likely diagnosis.
- Other Likely diagnoses
- Syphilis: This sexually transmitted infection can cause a variety of lesions, including painless ulcers (chancre) in its primary stage. Given its transmission route, it's a plausible cause for penile lesions.
- Genital warts (Human Papillomavirus): These are another common sexually transmitted infection that can lead to lesions on the penis. Their prevalence and the fact that they can cause visible growths make them a likely consideration.
- Balanitis: An inflammation of the glans (the rounded head of the penis), which can be caused by infections or irritations. It's common, especially in uncircumcised men, making it a reasonable differential diagnosis.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Penile cancer: Although rare, penile cancer can present with lesions. Early detection is crucial for treatment outcomes, making it essential not to miss this diagnosis.
- Lymphogranuloma venereum (LGV): A sexually transmitted infection caused by certain types of Chlamydia trachomatis. It can lead to serious complications if not treated promptly, including proctitis, lymphadenopathy, and genital ulcers.
- Rare diagnoses
- Behçet's disease: A rare disorder that can cause a variety of symptoms, including genital ulcers. While not common, its potential for serious complications warrants consideration in the differential diagnosis.
- Fixed drug eruption: A condition where certain medications can cause skin lesions, including on the genitals. It's less common but should be considered, especially if the patient has recently started new medications.