From the Guidelines
The mortality rate is approximately 1.1% among patients who underwent surgical resection of hepatic metastasis from gastric cancer, as reported in a study published in 2014 1. This rate is based on data from 15 studies, which included a total of 426 patients.
- The study found that mortality was 1.1% (5/426) among the patients who underwent surgical resection.
- Morbidity ranged from 19% to 47% among 6 studies. It's worth noting that the study was published in the journal Gastric Cancer, which is a reputable source in the field of gastroenterology. However, it's also important to consider that the study is from 2014, and more recent data may be available. Other studies, such as those on cardiovascular disease 1, lung cancer 1, Kawasaki disease 1, and rhinosinusitis and nasal polyps 1, report different mortality rates, but these are not directly relevant to the question of mortality rates among patients who underwent surgical resection of hepatic metastasis from gastric cancer. Therefore, based on the most recent and relevant evidence, the mortality rate for this specific patient population is approximately 1.1% 1.
From the Research
Mortality Rates
- The mortality rate for patients with community-acquired pneumonia was found to be 5.6% at 30 days 2.
- A study on patients hospitalized with community-acquired pneumonia found that the unadjusted 30-day mortality was 6.4% for those who received a beta-lactam plus doxycycline, compared to 9.1% for those who did not 3.
- The same study found that the 90-day mortality was 13.8% for those who received a beta-lactam plus doxycycline, compared to 16.8% for those who did not 3.
- In a propensity score matched model, both 30- and 90-day mortality were significantly lower for those who received doxycycline, with odds ratios of 0.72 and 0.83, respectively 3.
- A study on pneumococcal meningitis in infant rats found that adjuvant doxycycline therapy significantly reduced mortality, as well as blood-brain barrier disruption and cortical brain injury 4.
Disease-Specific Mortality Rates
- Human African trypanosomiasis (HAT), also known as sleeping sickness, is almost always fatal if untreated or inadequately treated 5.
- The mortality rate for HAT is not explicitly stated in the provided studies, but it is noted that the disease is highly fatal if left untreated 5.
Comparison of Mortality Rates
- The provided studies suggest that the use of doxycycline as part of combination therapy may be associated with lower mortality rates for patients with community-acquired pneumonia 3, 2.
- However, more research is needed to confirm this association and to determine the optimal treatment regimens for different patient populations 3.