From the Guidelines
Taking vitamin K2 supplements is generally recommended for many adults, particularly those with specific health concerns like bone or cardiovascular health issues, while boron supplementation is less clearly established as necessary. When considering supplementation, it's essential to prioritize the most recent and highest quality evidence. According to the most recent study 1, vitamin K2 supplementation is recommended, especially for individuals with a history of bariatric surgery or those at risk of nutritional deficiencies. The recommended daily dose of vitamin K2 is not explicitly stated in the provided evidence, but typical supplemental doses range from 45-180 mcg daily, with MK-7 being the preferred form due to its longer half-life in the body. For boron, the evidence is less robust, and most people can obtain sufficient boron through a diet rich in fruits, vegetables, and nuts. However, boron supplements typically range from 3-6 mg daily when used. It's crucial to note that vitamin K2 works by activating proteins that direct calcium to bones rather than arteries, potentially improving bone density and reducing arterial calcification. Those taking blood thinners like warfarin should avoid K2 supplements without medical supervision. Before starting either supplement, consulting with a healthcare provider is advisable, especially if you have existing health conditions or take medications. The healthcare provider can help determine the best course of action and recommend the appropriate dosage based on individual needs. In terms of specific recommendations, the study 1 suggests that vitamin K supplementation should be considered, especially for individuals with a history of bariatric surgery or those at risk of nutritional deficiencies. The study recommends a daily dose of 90-120 μg of vitamin K. Ultimately, the decision to take vitamin K2 and boron supplements should be made in consultation with a healthcare provider, taking into account individual health needs and circumstances.
From the FDA Drug Label
Description: Pure Vita Vitamin D3 (Cholecalciferol) and Vitamin K2 (Menatetrenone-MK4) work together to support bone helath, calcium absorption and heart health. The FDA drug label does not answer the question.
From the Research
Vitamin K2 and Boron Supplementation
- The effectiveness of boron supplementation on bone health has been evaluated in several studies, with results suggesting that a daily dosage of 3 mg/day of boron can be useful in supporting bone health 2.
- Vitamin K2 has been shown to play a crucial role in bone metabolism, with low intake linked to bone loss and increased fracture risk 3.
- Vitamin K2 supplementation has been recognized as efficacious and safe in the treatment of bone loss, and may be used alone or with other drugs to preserve bone quality and strength 3.
- The combination of vitamin K2 and boron supplementation may have a synergistic effect on bone health, although more research is needed to confirm this.
Potential Benefits and Interactions
- Vitamin K2 has been shown to inhibit arterial calcification and arterial stiffening, and may lower the risk of vascular damage 4.
- Boron supplementation has been found to have a positive effect on bone health, particularly when combined with other micronutrients such as calcium and vitamin D 2.
- However, high doses of vitamin K2 may interact with warfarin, a common anticoagulant medication, and reduce its effectiveness 5.
- The interaction between vitamin K2 and boron supplementation is not well understood, and more research is needed to determine the potential benefits and risks of combining these supplements 2, 3.