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Last updated: June 26, 2025View editorial policy

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Differential Diagnosis for Fluid-Filled Terminal Ileum in CECT

Single Most Likely Diagnosis

  • Small Bowel Obstruction: This is the most likely diagnosis because a fluid-filled terminal ileum is a common finding in small bowel obstruction, where the ileum becomes dilated with fluid due to a mechanical blockage preventing normal flow of intestinal contents.

Other Likely Diagnoses

  • Ileus: Postoperative or adynamic ileus can cause a fluid-filled terminal ileum due to decreased motility of the bowel, leading to accumulation of fluid.
  • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease can cause inflammation and narrowing of the ileum, potentially leading to a fluid-filled appearance on CECT due to obstruction or decreased motility.
  • Infection: Infectious ileitis, such as that caused by Salmonella or Yersinia, can lead to inflammation and fluid accumulation in the terminal ileum.

Do Not Miss Diagnoses

  • Intussusception: Although less common in adults, intussusception can cause a fluid-filled terminal ileum and is a critical diagnosis not to miss due to the risk of bowel ischemia and necrosis.
  • Volvulus: A volvulus of the small bowel can cause obstruction and a fluid-filled appearance of the terminal ileum, requiring prompt diagnosis and treatment to prevent ischemia.
  • Ischemic Bowel: Ischemia of the bowel can lead to a fluid-filled terminal ileum due to decreased motility and inflammation, and is a critical diagnosis due to the high risk of bowel necrosis and perforation.

Rare Diagnoses

  • Lymphoma: Although rare, lymphoma involving the terminal ileum can cause obstruction and a fluid-filled appearance on CECT.
  • Carcinoid Tumor: A carcinoid tumor in the terminal ileum can cause obstruction and fluid accumulation, and is an important diagnosis to consider due to its potential for malignancy.
  • Meckel's Diverticulum: A complication of Meckel's diverticulum, such as obstruction or inflammation, can lead to a fluid-filled terminal ileum, although this is a rare cause.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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