What are the symptoms and treatment for a positive Cladosporium herbarum Immunoglobulin G (IgG) test result?

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Last updated: June 26, 2025View editorial policy

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From the Research

A positive Cladosporium herbarum IgG test result indicates previous exposure to this common mold, and treatment should focus on reducing mold exposure and managing symptoms. Symptoms may include respiratory issues like coughing, wheezing, and nasal congestion, particularly in allergic individuals. Some people may experience skin reactions, headaches, or fatigue with significant exposure. Treatment typically begins with reducing mold exposure through environmental control measures such as improving ventilation, using dehumidifiers, and cleaning visible mold. For symptomatic individuals, antihistamines like loratadine (10mg daily) or cetirizine (10mg daily) can help manage allergic reactions, as suggested by general medical knowledge and not specifically by 1, 2, 3, 4, 5. Nasal corticosteroids such as fluticasone (1-2 sprays per nostril daily) may reduce nasal inflammation. In severe cases, oral corticosteroids might be prescribed for short courses. Immunotherapy could be considered for long-term management in persistently symptomatic patients, with a study from 2 suggesting its potential efficacy for allergic fungal respiratory diseases, including those caused by Cladosporium herbarum. It's essential to understand that IgG antibodies indicate exposure rather than active allergy, which is typically measured by IgE antibodies. If you're experiencing symptoms, consult with an allergist who can determine if your symptoms are related to Cladosporium exposure or another condition requiring different treatment. Key considerations in management include:

  • Reducing mold exposure
  • Managing symptoms with antihistamines or nasal corticosteroids
  • Considering immunotherapy for long-term management
  • Consulting an allergist for personalized advice, based on the most recent and highest quality study available, which in this context is 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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