Is it safe to apply Latisse (bimatoprost) to the axilla to promote hair growth?

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Last updated: June 26, 2025View editorial policy

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From the Guidelines

No, it is not safe to apply Latisse (bimatoprost) to the axilla to promote hair growth. Latisse is FDA-approved only for application to the upper eyelid margins to treat hypotrichosis (inadequate eyelashes) [ 1 ]. Using it in the underarm area is considered off-label and has not been studied for safety or efficacy in this location. The skin in the axilla differs significantly from eyelid skin, being thicker and containing more sweat glands, which could affect absorption and potentially increase side effects.

Some key points to consider:

  • Bimatoprost ophthalmic solution may result in growth of eyelashes in some patients but is not generally recommended for this purpose [ 1 ].
  • Minoxidil can be considered to stimulate hair growth after CIA or EIA [ 1 ].
  • The use of bimatoprost for promoting hair growth in areas other than the eyelashes is not supported by strong evidence [ 1 ].

Given the potential risks and lack of evidence supporting its use for underarm hair growth, it is recommended to consult with a dermatologist for approved treatments. Common side effects of Latisse even when used as directed include skin darkening, eye irritation, and dryness [ 1 ]. When applied to larger areas like the underarm, there's an increased risk of these side effects and potentially others that haven't been studied.

From the Research

Safety of Applying Latisse to the Axilla

  • There are no research papers that directly assess the safety of applying Latisse (bimatoprost) to the axilla to promote hair growth 2, 3, 4, 5, 6.
  • The available studies focus on the use of bimatoprost for the treatment of eyelash hypotrichosis, with applications limited to the eyelid margin 2, 3, 5, 6.
  • One study reports the use of topical bimatoprost for the treatment of eyebrow hypotrichosis, but its application to other areas, such as the axilla, is not mentioned 4.
  • The safety profile of bimatoprost when applied to the eyelid margin is generally favorable, with common adverse events including conjunctival hyperemia, eyelid pruritus, and blepharal pigmentation 3, 6.
  • However, the safety of applying bimatoprost to the axilla is unknown, and its use in this area is considered off-label.

Potential Risks and Considerations

  • Applying bimatoprost to the axilla may pose unknown risks, as the skin and hair follicles in this area may respond differently to the medication compared to the eyelid margin.
  • The potential for systemic absorption and side effects should be considered, although dermal application of bimatoprost appears to be associated with a lower incidence of adverse events compared to ocular administration 5.
  • Patients should be informed of the potential risks and benefits of using bimatoprost for off-label purposes, and alternative treatments for axillary hair growth should be discussed.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Bimatoprost in the treatment of eyelash hypotrichosis.

Clinical ophthalmology (Auckland, N.Z.), 2010

Research

Topical bimatoprost for the treatment of eyebrow hypotrichosis.

Journal of drugs in dermatology : JDD, 2012

Research

Management of hypotrichosis of the eyelashes: Focus on bimatoprost.

Clinical, cosmetic and investigational dermatology, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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