Is Valium (diazepam) recommended as a premedication for patients undergoing Intrauterine Device (IUD) insertion?

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Last updated: June 26, 2025View editorial policy

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From the Research

Valium (diazepam) is not recommended as a standard premedication for IUD insertion due to its limited efficacy in addressing pain and potential risks, including sedation and respiratory depression. The most recent and highest quality study, 1, does not support the use of Valium for IUD insertion, and instead, highlights the importance of conscious sedation options, such as nitrous gas or intravenous midazolam and fentanyl, for patients undergoing the procedure.

For pain management during IUD insertion, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (400-800mg) taken 30-60 minutes before the procedure are more commonly recommended, as seen in studies such as 2. However, even ibuprofen has been shown to have limited efficacy in reducing pain associated with IUD insertion, with a randomized trial finding no significant difference in pain scores between ibuprofen and placebo groups 2.

Diazepam primarily addresses anxiety rather than pain and carries risks including sedation, respiratory depression, and potential for dependence. It also requires monitoring after administration and patients would need someone to drive them home afterward. Additionally, the anxiolytic effects may not significantly improve the overall IUD insertion experience for most patients. Non-pharmacological approaches such as verbal reassurance, distraction techniques, and having a supportive person present during the procedure are often more appropriate for managing anxiety related to IUD insertion.

Some key points to consider when managing pain and anxiety during IUD insertion include:

  • The use of conscious sedation options, such as nitrous gas or intravenous midazolam and fentanyl, for patients undergoing the procedure 1
  • The limited efficacy of NSAIDs, such as ibuprofen, in reducing pain associated with IUD insertion 2
  • The potential risks and benefits of using diazepam for anxiety management during IUD insertion
  • The importance of non-pharmacological approaches, such as verbal reassurance and distraction techniques, in managing anxiety related to IUD insertion.

If severe anxiety is a concern, consultation with a healthcare provider about individualized options is recommended before the appointment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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