What are the recommended instructions for using a Freestyle Libre (Flash Glucose Monitoring System) on a prescription?

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Last updated: June 26, 2025View editorial policy

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From the Guidelines

To use a Freestyle Libre Flash Glucose Monitoring System as prescribed, apply the sensor to the back of your upper arm after cleaning the area with alcohol, and scan the sensor with the reader or compatible smartphone app at least once every 8 hours for complete data collection, as recommended by recent studies 1. The system is designed to provide current glucose level, trend arrow, and 8-hour history, and it eliminates the need for routine fingerstick testing, though blood glucose testing may be required during times of rapidly changing glucose levels, when symptoms don't match readings, or to confirm hypoglycemia. Key points to consider when using the Freestyle Libre include:

  • The sensor lasts for 14 days and is water-resistant for up to 30 minutes at a depth of 1 meter 1.
  • The system works by measuring glucose in interstitial fluid rather than blood, which causes a 5-10 minute physiological lag behind actual blood glucose levels, important to consider when glucose is changing rapidly 1.
  • Studies have shown that the Freestyle Libre can reduce time spent in hypoglycemia and hyperglycemia, and it may be particularly beneficial for patients with type 1 diabetes and hypoglycemia unawareness 1. It is essential to follow the manufacturer's instructions and consult with a healthcare provider for personalized guidance on using the Freestyle Libre Flash Glucose Monitoring System, as the accuracy of the system may be lower at high and low glucose levels 1.

From the Research

Recommended Instructions for Using a Freestyle Libre on a Prescription

The FreeStyle Libre flash glucose monitor is a device designed to replace the need for frequent finger-stick blood glucose tests in individuals with diabetes. Here are some key points to consider when using a FreeStyle Libre on a prescription:

  • The device is calibration-free and consists of a disc worn on the arm for 14 days 2.
  • It is essential to follow the manufacturer's instructions for applying and using the device to ensure accurate glucose readings.
  • The FreeStyle Libre has been shown to be accurate and reliable in clinical trials, with a mean absolute relative difference (MARD) of 16.7% compared to capillary blood glucose measurements in children with type 1 diabetes 3.
  • The device can be worn on alternative sites, such as the lower back or anterior chest, although the accuracy may vary depending on the site and individual 4.
  • It is crucial to educate both users and healthcare professionals on the proper use and interpretation of the FreeStyle Libre to harness its full benefits 2.

Potential Adverse Events and Considerations

When using a FreeStyle Libre, there are some potential adverse events and considerations to be aware of:

  • Allergic contact dermatitis caused by isobornyl acrylate in the adhesive part of the sensor has been reported 5.
  • Sensor problems, such as early detachment, have been observed in some patients 3.
  • The accuracy of the device may be affected by factors such as skin temperature, exercise, and glucose concentration 4.
  • It is essential to follow the manufacturer's guidelines for troubleshooting and resolving any issues that may arise during use.

Tips for Optimal Use

To get the most out of a FreeStyle Libre, consider the following tips:

  • Ensure proper application and adhesion of the sensor to the skin.
  • Scan the sensor regularly to obtain accurate glucose readings.
  • Use the device in conjunction with other diabetes management tools, such as insulin therapy and lifestyle modifications.
  • Consult with a healthcare professional if you have any questions or concerns about using the FreeStyle Libre 2, 3, 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Flash forward: a review of flash glucose monitoring.

Diabetic medicine : a journal of the British Diabetic Association, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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