Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 26, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Testicular Swelling

Single Most Likely Diagnosis

  • Epididymitis: This is an inflammation of the epididymis, a tube at the back of the testicle that stores and carries sperm. It's often caused by a bacterial infection and is a common cause of testicular swelling, especially in young men.

Other Likely Diagnoses

  • Orchitis: Inflammation of one or both testicles, usually caused by bacterial or viral infections. It can occur alone or in combination with epididymitis (epididymo-orchitis).
  • Hydrocele: A condition where fluid accumulates in the scrotum, causing swelling of the testicle. It can be primary (idiopathic) or secondary due to other conditions like injury, infection, or tumor.
  • Varicocele: An enlargement of the veins within the scrotum, similar to varicose veins. It's more common on the left side and can cause swelling and a feeling of heaviness.

Do Not Miss Diagnoses

  • Testicular Torsion: A medical emergency where the spermatic cord becomes twisted, cutting off the blood supply to the testicle. It requires immediate surgical intervention to save the testicle.
  • Testicular Cancer: Although less common, testicular cancer can present with swelling, a lump, or a feeling of heaviness in the scrotum. Early detection is crucial for effective treatment.

Rare Diagnoses

  • Spermatocele: A cystic structure that forms at the head of the epididymis and contains sperm. It's usually benign and may cause swelling but is less common.
  • Cystic dysplasia of the testis: A rare congenital anomaly where cysts form within the testicle, leading to swelling.
  • Henoch-Schönlein Purpura (HSP): A form of vasculitis that can affect various parts of the body, including the testicles, leading to swelling and pain. It's more common in children.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.