Is vitamin K (Vit K) important for bone health?

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From the Research

Vitamin K is crucial for bone health, and its importance cannot be overstated, as it plays a significant role in regulating calcium in bones and preventing calcium loss, thereby reducing the risk of osteoporosis. The most recent and highest quality study, 1, published in 2024, highlights the importance of vitamin K and its combination with vitamin D for calcium metabolism and bone health. This study emphasizes that an adequate vitamin K status is required for the carboxylation of osteocalcin and matrix Gla-protein (MGP), which are essential for bone mineralization and strength.

Key points to consider:

  • Vitamin K activates osteocalcin, a protein that binds calcium to the bone matrix, and also inhibits osteoclasts, the cells that break down bone tissue.
  • There are two main forms of vitamin K: K1 (phylloquinone), found in green leafy vegetables like kale, spinach, and broccoli; and K2 (menaquinone), found in fermented foods like natto, cheese, and animal products.
  • For adults, the recommended daily intake is about 90-120 micrograms, as suggested by 2.
  • Vitamin K works synergistically with vitamin D and calcium to maintain bone density, making it particularly important for preventing osteoporosis, especially in postmenopausal women and older adults, as noted in 3 and 1.
  • While most people get sufficient vitamin K from their diet, those with malabsorption disorders, those on long-term antibiotics, or those taking blood thinners like warfarin should discuss vitamin K intake with their healthcare provider, as mentioned in the example answers.

It is essential to prioritize vitamin K intake, particularly among institutionalized elderly people, to prevent increased bone resorption, as highlighted in 4. However, it is crucial to rely on the most recent and highest quality study, 1, which provides the most up-to-date information on the importance of vitamin K for bone health.

References

Research

Vitamin K and bone health.

Nutrition (Burbank, Los Angeles County, Calif.), 2001

Research

Bone health. New role for vitamin K?

Canadian family physician Medecin de famille canadien, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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