What is the recommended dose of Nasonex (mometasone furoate)?

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From the Guidelines

The recommended dose of Nasonex (mometasone furoate) is 2 sprays per nostril every day for adults and children 12 years and older, and 1 spray per nostril every day for children 2-11 years old. According to the clinical practice guideline on allergic rhinitis 1, the dosing for Nasonex is as follows:

  • Age 2-11 y: 1 spray per nostril every day
  • Age ≥12 y: 2 sprays per nostril every day
  • Age ≥18 y with polyps: 2 sprays per nostril twice a day It is essential to follow the prescribed dosage and administration instructions to achieve the best results and minimize potential side effects, such as headache, viral infection, pharyngitis, epistaxis, and cough, as listed in the guideline 1. Some key points to consider when using Nasonex include:
  • Priming the bottle before first use by pumping 10 times or until a fine mist appears
  • Repriming the spray with 2 sprays if it hasn't been used for more than 7 days
  • Shaking the bottle gently before each use
  • Blowing your nose to clear nasal passages before spraying
  • Breathing in gently through the nose and out through the mouth after spraying By following the recommended dose and administration instructions, patients can effectively manage their allergic rhinitis symptoms and improve their quality of life.

From the FDA Drug Label

Use one spray in each nostril once daily. Users age 12 or older Use two sprays in each nostril every day. The recommended dose of Nasonex (mometasone furoate) is:

  • For children age 2 to 11: one spray in each nostril once daily.
  • For users age 12 or older: two sprays in each nostril every day 2.

From the Research

Nasonex Dose Information

The recommended dose of Nasonex (mometasone furoate) varies depending on the patient's age and condition.

  • For children 6 to 11 years of age with seasonal allergic rhinitis, the recommended dose is 100 microgram once daily 3.
  • For patients 12 years and older with seasonal allergic rhinitis, the recommended dose is 200 microgram once daily 4.
  • For patients 12 years and older with perennial allergic rhinitis, the recommended dose is 200 microgram once daily 5.
  • For acute recurrent sinusitis, the dose is 400 microgram twice daily 6.

Special Considerations

  • The dose of 100 microgram once daily is sufficient for children 6 to 11 years of age, and higher doses do not provide additional benefits 3.
  • The dose of 200 microgram once daily is effective for patients 12 years and older with seasonal allergic rhinitis, and higher doses do not provide significant additional benefits 4.
  • Nasonex is well tolerated at all doses, with no evidence of hypothalamic-pituitary-adrenal axis suppression 3, 6, 4, 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Dose ranging study of mometasone furoate (Nasonex) in seasonal allergic rhinitis.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997

Research

Once daily mometasone furoate aqueous nasal spray is as effective as twice daily beclomethasone dipropionate for treating perennial allergic rhinitis patients.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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