What is the treatment for a calcium ring in the eye, also known as calcific band keratopathy?

From the Guidelines

Treatment for calcific band keratopathy, also known as a calcium ring in the eye, typically involves chelation therapy with EDTA (ethylenediaminetetraacetic acid), which removes calcium deposits from the cornea, as recommended by the most recent study 1. The procedure, called EDTA chelation, is performed by an ophthalmologist who applies EDTA solution to the affected area after removing the overlying epithelium. This chemical binds to calcium deposits and helps dissolve them. Some key points to consider in the treatment of calcific band keratopathy include:

• The use of EDTA chelation therapy, which has been shown to be effective in removing calcium deposits from the cornea 1
• The importance of addressing underlying causes of the condition, such as chronic eye inflammation, hypercalcemia, or chronic dry eye, to prevent recurrence 1
• The potential need for additional procedures, such as superficial keratectomy or phototherapeutic keratectomy (PTK), in severe cases 1
• The use of a bandage contact lens and antibiotic eye drops to promote healing and prevent infection after treatment 1 It's worth noting that the treatment approach may vary depending on the density of the calcium deposits and the individual patient's needs, as highlighted in the study 1. Overall, the goal of treatment is to remove the calcium deposits, restore vision and comfort, and prevent recurrence, with the most recent study 1 providing the most up-to-date guidance on the best approach.

From the Research

Treatment for Calcific Band Keratopathy

The treatment for calcific band keratopathy, also known as a calcium ring in the eye, is not directly addressed in the provided studies. However, the studies discuss the treatment of hypercalcemia, which can be related to the condition.

Hypercalcemia Treatment

• The treatment for hypercalcemia includes fluid repletion and intravenous administration of bisphosphonates 2, 3.
• Bisphosphonates, such as pamidronate and zoledronate, are effective in normalizing serum calcium levels 2, 3.
• Other treatments, such as calcitonin and gallium nitrate, may also be used in certain cases 2.

Ocular Calcification

• Ocular calcification, including corneal and conjunctival calcification, can be associated with chronic renal failure and hyperparathyroidism 4.
• Lid lesions, including calcified deposits, can occur in patients with systemic diseases such as chronic renal failure and hyperparathyroidism 4.

Sarcoidosis and Hypercalcemia

• Sarcoidosis can cause hypercalcemia and ocular manifestations, including retinal detachment 5.
• Prompt therapy with steroids is indicated in cases of sarcoidosis with symptomatic hypercalcemia 5.

Important Considerations

• Renal dysfunction and vitamin D deficiency should be evaluated before bisphosphonate treatment 6.
• Accurate monitoring of plasma calcium and creatinine levels is necessary during bisphosphonate treatment 6.
• Vitamin D and calcium supply may be necessary during treatment with bisphosphonates 6.