Is the 111skin (retinol) wrinkle erasing patch effective for reducing fine lines and wrinkles?

From the Guidelines

The 111skin retinol wrinkle erasing patch is likely to have a modest benefit in reducing fine lines and wrinkles, but its effectiveness is limited compared to traditional retinol products. The patch contains retinol, a vitamin A derivative that stimulates collagen production and increases cell turnover, which can help reduce the appearance of wrinkles over time 1. However, the patch format means the retinol only works on the specific area where applied and for the limited time the patch is worn.

Key Points to Consider

• The British Association of Dermatologists' guidelines suggest that topical retinoids, such as retinol, can lend some additional benefit with respect to improvement in lentigines and reduced wrinkles 1.
• Traditional retinol products, such as adapalene 0.3%, tretinoin 0.1% and 0.05%, and topical isotretinoin 0.1%, have been shown to be effective in reducing fine lines and wrinkles when used consistently over time 1.
• The patch format of the 111skin retinol wrinkle erasing patch may be useful for special occasions when a temporary improvement is desired or for targeting specific expression lines, but it should not replace a comprehensive skincare routine.

Limitations and Considerations

• The high price point of the 111skin retinol wrinkle erasing patch makes it an expensive option compared to traditional retinol products that may provide better long-term results when used regularly.
• The limited duration of action of the patch may require frequent reapplication, which can be inconvenient and may not provide the same level of consistent improvement as traditional retinol products.

From the Research

Effectiveness of 111skin Wrinkle Erasing Retinol Patch

• The effectiveness of the 111skin wrinkle erasing retinol patch in reducing fine lines and wrinkles can be inferred from studies on retinol and its effects on skin aging 2, 3, 4, 5, 6.
• Retinol has been shown to improve fine lines and wrinkles, hyperpigmentation, skin roughness, and the appearance of photoaged skin 3.
• A study on a novel cosmetic containing retinol found significant improvement in wrinkles at the corners of the eyes, with 34% of subjects showing marked or moderate improvement 4.
• Another study on a retinol and cannabidiol combination topical found global improvement across all 13 domains, including visible pores, dehydration, roughness, and static/dynamic wrinkles 5.
• A study on retinyl retinoate-loaded dissolving microneedle patches found statistically significant differences in all Visiometer R-values, indicating wrinkle improvement 6.

Key Findings

• Retinol is effective in improving fine lines and wrinkles, and its efficacy is supported by multiple studies 2, 3, 4, 5, 6.
• The combination of retinol with other ingredients, such as cannabidiol, may enhance its effects and reduce irritation 5.
• Novel delivery systems, such as dissolving microneedle patches, may improve the efficacy and usability of retinol-based products 6.

Mechanism of Action

• Retinol works by promoting cell turnover, increasing collagen production, and improving skin elasticity, leading to a reduction in fine lines and wrinkles 3.
• The exact mechanism of action of the 111skin wrinkle erasing retinol patch is not specified, but it is likely to involve similar pathways as other retinol-based products 2, 3, 4, 5, 6.