From the Research
The most effective treatment for acanthosis nigricans (AN) around the eyes is addressing the underlying cause, such as weight loss and improved blood glucose control, along with topical treatments like retinoids or alpha hydroxy acids, as supported by the most recent study 1. The treatment approach for AN around the eyes should prioritize the management of underlying metabolic conditions, which are often the root cause of this skin condition.
- Weight loss and improved blood glucose control through diet modifications and increased physical activity are crucial in managing AN.
- Topical treatments, such as retinoids like tretinoin 0.05% cream applied once daily, or alpha hydroxy acids like 12% ammonium lactate lotion twice daily, can help improve the appearance of AN lesions by increasing cell turnover and reducing hyperpigmentation.
- For more resistant cases, prescription-strength retinoids or low-concentration topical corticosteroids might be recommended, but these should be used cautiously around the eyes and only under medical supervision due to the thin skin in this area.
- Procedures like microdermabrasion or chemical peels may also help in some cases, as noted in studies like 2 and 3. It's essential to understand that treatment results are often gradual, and complete resolution typically depends on successful management of the underlying metabolic condition, as highlighted in 4 and 5. Regular follow-up with healthcare providers is necessary to monitor both the skin condition and any associated systemic disorders.