Is bakuchiol contraindicated in pregnancy?

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Last updated: June 28, 2025View editorial policy

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From the Research

Bakuchiol is generally not recommended during pregnancy due to limited safety data. While bakuchiol is often marketed as a natural retinol alternative, there are insufficient studies evaluating its safety in pregnant women, as noted in a systematic review of human clinical trials using topical bakuchiol formulations 1. Unlike some skincare ingredients that have been definitively proven unsafe during pregnancy (such as retinoids), bakuchiol lacks robust research confirming either its safety or risk. The concern stems from bakuchiol's ability to mimic some of retinol's effects on skin cells, potentially affecting cell development.

Some key points to consider include:

  • Bakuchiol has been shown to have anti-aging effects and improve photoageing, with similar efficacy to retinol in some studies 2, 3
  • However, the majority of studies on bakuchiol have methodologic limitations and introduce a high risk of bias in reported outcomes 1
  • There is limited information available on the use of bakuchiol during pregnancy and breastfeeding, and its effects on the fetus or baby are not well understood
  • Other skincare ingredients, such as glycerin, hyaluronic acid, and vitamin C, have established safety profiles and may be safer alternatives for pregnant women

Since pregnancy is a time when many healthcare providers recommend a cautious approach to skincare ingredients, it's advisable to avoid bakuchiol during pregnancy and breastfeeding. Instead, pregnant women should consider using skincare ingredients with established safety profiles. Always consult with a healthcare provider before using any skincare products during pregnancy, as individual circumstances may vary. Recent studies, such as the 2024 systematic review 1, highlight the need for further research on the safety and efficacy of bakuchiol, particularly in vulnerable populations like pregnant women.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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