From the Guidelines
The treatment for intertrigo involves using topical azoles and polyenes, including clotrimazole, miconazole, and nystatin, and keeping the area dry, especially in obese and diabetic patients. When managing intertrigo, it is crucial to consider the patient's overall health and potential contributing factors such as obesity and diabetes. Key aspects of treatment include:
- Using topical antifungal agents like clotrimazole, miconazole, and nystatin, as recommended by the Infectious Diseases Society of America 1.
- Keeping the affected skin folds clean and dry to prevent moisture accumulation, which can exacerbate the condition.
- Reducing friction between skin folds, which can be achieved by using absorbent cotton clothing and placing soft cotton cloth between skin folds.
- In some cases, weight loss may be beneficial in reducing recurrence, particularly in overweight individuals. It is essential to note that intertrigo can be caused by various microorganisms, and the treatment should be tailored to the specific cause, with fungal infections being commonly treated with topical antifungals like clotrimazole 1% cream twice daily for 2-4 weeks, as suggested by guidelines 1.
From the Research
Treatment for Intertrigo
The treatment for intertrigo involves a combination of measures to reduce moisture, friction, and secondary infections. Some of the key approaches include:
- Minimizing moisture and friction with absorptive powders such as cornstarch or with barrier creams 2
- Wearing light, nonconstricting, and absorbent clothing and avoiding wool and synthetic fibers 2
- Educating patients about precautions with regard to heat, humidity, and outside activities 2
- Treating secondary bacterial and fungal infections with antiseptics, antibiotics, or antifungals, depending on the pathogens 2, 3
- Using moisture-wicking textiles within skin folds to reduce skin-on-skin friction, wick away moisture, and reduce secondary infection 4
- Adopting a structured skin care routine and managing skin folds to prevent intertrigo 4
Topical Antifungal Agents
Topical antifungal agents are commonly used to treat intertrigo, particularly when caused by fungal infections. Some of the topical antifungal agents used include:
- Amphotericin B or nystatin for oropharyngeal candidiasis 5
- Imidazoles such as clotrimazole or miconazole for Candida intertrigo 5
- Azoles or selenium sulphur for infections caused by Malassezia spp. 5
- Terbinafine or tolnaftate for intertrigo and tinea corporis 5
Secondary Infections
Secondary infections, such as bacterial or fungal infections, can occur in intertrigo. These infections can be treated with: