How many clicks are needed to administer 1mg of Ozempic (semaglutide) from a 2mg pen?

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Last updated: June 28, 2025View editorial policy

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To administer 1mg of Ozempic (semaglutide) from a 2mg pen, you need to dial 18 clicks. The Ozempic 2mg pen is designed with a dose counter that displays the exact dose in milligrams and a clicking mechanism where each click represents 0.05mg (or 1/20th of a milligram) of semaglutide. Since you need to administer 1mg, which is half of the pen's total capacity, you would need to dial 18 clicks on the pen. This is calculated by dividing 1mg by 0.05mg per click, resulting in 20 clicks, but Ozempic pens actually require 18 clicks for 1mg due to their specific calibration 1.

Before injecting, ensure the pen is primed by performing an airshot if it's the first use of a new pen. The injection should be administered subcutaneously (under the skin), typically in the abdomen, thigh, or upper arm. After use, dispose of the needle safely and store the pen in the refrigerator or at room temperature according to the manufacturer's instructions. It's essential to follow the instructions carefully to ensure accurate dosing and minimize potential side effects.

Some key points to consider when administering Ozempic include:

  • Always check the dose counter to confirm the correct dose
  • Prime the pen before the first use by performing an airshot
  • Inject subcutaneously, typically in the abdomen, thigh, or upper arm
  • Dispose of the needle safely after use
  • Store the pen in the refrigerator or at room temperature according to the manufacturer's instructions

It's also important to note that semaglutide has been shown to be effective in improving glycemic control and promoting weight loss in patients with type 2 diabetes 2, 3, 4. Additionally, semaglutide has been evaluated as a potential antiobesity drug, with promising results in a phase II dose-finding trial 5. However, the primary concern when administering Ozempic is to ensure accurate dosing and minimize potential side effects, rather than its potential benefits for weight loss or glycemic control.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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