How many clicks of an Ozempic (semaglutide) pen, which delivers 8mg per 3ml, are needed to administer a 1mg dose?

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Last updated: June 28, 2025View editorial policy

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From the FDA Drug Label

Your pen is a prefilled, single-patient-use, dial-a-dose pen. It contains 4 mg of semaglutide, and you can only select doses of 1 mg Each prefilled pen contains 4 doses of 1 mg.

To deliver a 1 mg dose, 1 click of the Ozempic pen is needed, as the pen delivers doses in 1 mg increments only 1.

From the Research

To administer a 1mg dose of Ozempic (semaglutide) using an 8mg/3ml pen, you need to dial 12 clicks. Each Ozempic pen is calibrated so that one click delivers a specific amount of medication. For the 8mg/3ml pen, each click delivers approximately 0.083mg of semaglutide (8mg ÷ 96 clicks total = 0.083mg per click). Therefore, to reach a 1mg dose, you need 12 clicks (1mg ÷ 0.083mg = 12 clicks). When administering Ozempic, ensure the pen needle is attached properly, perform an airshot before first use of a new pen, and inject subcutaneously into the abdomen, thigh, or upper arm. Hold the needle in place for 6 seconds after pressing the dose button completely to ensure the full dose is delivered. This click-based dosing system allows for precise administration of semaglutide, which is important because the medication needs to be carefully titrated to minimize gastrointestinal side effects while achieving glycemic control, as seen in studies such as 2 and 3. The precise dosing is crucial for maximizing the efficacy of semaglutide while minimizing its side effects, as highlighted in the context of its use for weight management and cardiovascular risk reduction 4, 2, 3. However, the provided studies 5, 6 do not directly relate to the dosing of Ozempic but emphasize the importance of accurate dosing and administration techniques in medical practice. Given the information and the context of Ozempic administration, the focus remains on the precise calculation of clicks needed for a 1mg dose based on the pen's calibration.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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