What is the recommended daily dose of zinc supplement for adults?

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From the Guidelines

The recommended daily dose of zinc supplement for adults is 7.5-12.7 mg per day, with an additional 2.9 mg/day recommended for lactating women. This recommendation is based on the population reference intake for zinc for adult women, as established by the European Food Safety Authority (EFSA) in 2014 1. The EFSA recommends a population reference intake of 7.5-12.7 mg/day for adult women, which is derived from the zinc requirement of individuals with a body weight at the 97.5th percentile for reference weights for women. For lactating women, an additional 2.9 mg/day is recommended to account for the transfer of zinc into breast milk.

Some key points to consider when taking zinc supplements include:

  • The adequate intake for adults is 7.5-12.7 mg/day, with an additional 2.9 mg/day for lactating women
  • Zinc supplements are typically available in higher doses, but most adults should not exceed 40 mg of zinc daily from all sources combined
  • Zinc is essential for immune function, wound healing, DNA synthesis, and protein production in the body
  • Most healthy adults can obtain sufficient zinc through a balanced diet that includes foods like oysters, red meat, poultry, beans, nuts, and fortified cereals
  • Supplementation is primarily beneficial for those with inadequate dietary intake, absorption issues, or certain health conditions

It's also important to note that high doses of zinc may cause adverse effects, such as nausea, vomiting, loss of appetite, or interfere with copper absorption. If you have any underlying health conditions or take medications, it's recommended to consult with a healthcare provider before starting zinc supplementation. Additionally, taking zinc supplements with food can help reduce stomach irritation. Overall, the recommended daily dose of zinc supplement for adults is 7.5-12.7 mg per day, with an additional 2.9 mg/day recommended for lactating women, as established by the EFSA in 2014 1.

From the Research

Recommended Daily Dose of Zinc Supplement for Adults

The recommended daily dose of zinc supplement for adults is a topic of discussion among experts, with various organizations providing different guidelines.

  • The World Health Organization, the US Institute of Medicine, the International Zinc Nutrition Consultative Group, and the European Food Safety Agency have all set dietary zinc recommendations, but there are large discrepancies among them 2.
  • The US Institute of Medicine recommends a daily intake of 15 mg of zinc for adults, while other organizations may have slightly different recommendations 3.
  • It's worth noting that high intakes of zinc can cause copper deficiency, and the proximity of the recommended dietary allowance (RDA) and the reference dose (RfD) for safe intake of zinc is relatively narrow 4.
  • Some studies suggest that even lower levels of zinc supplementation, closer to the RDA, can interfere with the utilization of copper and iron and adversely affect HDL cholesterol concentrations 3.
  • The European Food Safety Agency sets dietary zinc recommendations at different levels of dietary phytate for adults, but not for children, and has not set a tolerable upper intake level for any life-stage group 2.

Factors Affecting Zinc Bioavailability

Several factors can affect the bioavailability of zinc from foods, including:

  • Fiber and phytate, which can impair zinc absorption 5.
  • The phytate:zinc molar ratio, which can be used to predict zinc bioavailability 5.
  • The total daily dietary zinc intake, which can affect the impact of phytate on zinc absorption 5.

Risks of Excessive Zinc Intake

Excessive zinc intake can cause several health problems, including:

  • Copper deficiency, which can lead to anemia and neutropenia 3.
  • Impaired immune function and adverse effects on the ratio of low-density-lipoprotein to high-density-lipoprotein (LDL/HDL) cholesterol 3.
  • Nausea, vomiting, epigastric pain, lethargy, and fatigue at extremely high zinc intakes 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A Review of Dietary Zinc Recommendations.

Food and nutrition bulletin, 2016

Research

Zinc toxicity.

The American journal of clinical nutrition, 1990

Research

Zinc requirements and the risks and benefits of zinc supplementation.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2006

Research

Zinc: requirements, bioavailabilities and recommended dietary allowances.

Progress in clinical and biological research, 1983

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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