From the Research
Four puffs of Symbicort (budesonide/formoterol) 80mcg is equivalent to two puffs of Symbicort 160mcg in terms of the total medication delivered, providing the same total dose of 320mcg of budesonide and the corresponding amount of formoterol. However, it's essential to follow the specific dosing prescribed by your healthcare provider, as they may have reasons for preferring one regimen over the other. The most recent and highest quality study, 1, demonstrates the efficacy and safety of budesonide/formoterol in reducing COPD exacerbations, but does not directly compare the two dosing regimens in question.
When considering the dosing regimen, it's crucial to take into account the potential for local side effects, such as thrush or hoarseness, which may be increased with more puffs (four instead of two). Proper inhaler administration technique is also vital for effective medication delivery, including shaking the inhaler before each puff, exhaling fully before inhaling, and rinsing the mouth after use to minimize side effects. If you're considering changing your dosing regimen, consult with your healthcare provider first to ensure it's appropriate for your specific condition.
Key points to consider:
- The total medication delivered is the same for both regimens
- Potential for increased local side effects with more puffs
- Proper inhaler administration technique is crucial
- Consult with your healthcare provider before changing your dosing regimen
- The most recent and highest quality study, 1, supports the use of budesonide/formoterol in reducing COPD exacerbations, but does not directly compare the two dosing regimens.