Is simethicone (anti-gas medication) syrup safe to drink during pregnancy?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Simethicone syrup is generally considered safe to drink during pregnancy. This anti-gas medication works by breaking up gas bubbles in the digestive tract and is not absorbed into the bloodstream, which means it doesn't reach the developing baby. Common brands include Gas-X, Mylicon, and store brands labeled as anti-gas medication. The typical adult dose is 40-125 mg after meals and at bedtime, not exceeding 500 mg daily. While simethicone can help relieve uncomfortable gas symptoms during pregnancy, it's always best to try non-medication approaches first, such as eating smaller meals, avoiding gas-producing foods, staying hydrated, and gentle exercise. If gas pain is severe or persistent, consult with your healthcare provider before starting any medication. The safety profile of simethicone during pregnancy is favorable because it acts locally in the digestive system rather than systemically, making it a reasonable option when lifestyle changes aren't providing sufficient relief from gas discomfort during pregnancy 1.

Some key points to consider:

  • Simethicone is not absorbed into the bloodstream, reducing the risk to the fetus
  • It acts locally in the digestive system, making it a safer option for pregnant women
  • Non-medication approaches should be tried first, such as dietary changes and gentle exercise
  • If medication is necessary, simethicone is a reasonable option due to its favorable safety profile
  • Consult with a healthcare provider before starting any medication during pregnancy.

It's essential to prioritize the health and well-being of both the mother and the fetus during pregnancy, and simethicone syrup can be a useful tool in managing gas discomfort when used under the guidance of a healthcare provider 1.

From the Research

Safety of Simethicone Syrup in Pregnancy

  • Simethicone is an anti-gas medication commonly used to relieve symptoms of gastroesophageal reflux disease (GERD) and other gastrointestinal disorders.
  • According to a study published in 2024 2, simethicone was found to be safe for use in healthy women, including pregnant women, when administered as part of an antacid suspension containing magaldrate.
  • The study found no absorption of aluminum and normal concentrations of magnesium in the blood samples of healthy volunteers who received the antacid, suggesting that the use of this antacid is safe and without risk in healthy women, including pregnant women.
  • Another study published in 2015 3 evaluated the effects of interventions for relieving heartburn in pregnancy and found that pharmaceutical treatment, including simethicone, compared with placebo or no treatment, resulted in complete heartburn relief more often in women who received pharmaceutical treatment.
  • However, it is essential to note that the evidence is limited, and more research is needed to fully evaluate the effectiveness and safety of simethicone syrup in pregnancy.

Precautions and Considerations

  • While simethicone syrup may be considered safe for use in pregnancy, it is crucial to follow the recommended dosage and consult with a healthcare provider before taking any medication during pregnancy.
  • Pregnant women should always prioritize their health and the health of their fetus by consulting with their healthcare provider before taking any medication, including simethicone syrup.
  • More research is needed to fully understand the effects of simethicone syrup in pregnancy, and pregnant women should be aware of the potential risks and benefits associated with its use.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.