From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Dioclear should be taken exactly as prescribed by your healthcare provider, with the most recent and highest quality study suggesting that bowel preparation agents like polyethylene glycol 3350 can be effective when administered with proper timing 1. Typically, it is taken orally with a full glass of water, with or without food. The standard dosage is usually one tablet daily, but this may vary based on your specific condition and medical history. It's essential to consider factors that may affect bowel preparation, such as health conditions, patient cognitive/behavioral characteristics, and medication use, as identified in a national survey 2. Additionally, a study on the evaluation of bowel preparation before colonoscopy by ultrasonographic monitoring of colonic fecal retention found that completion of bowel preparation can be assessed by the observation of anechoic areas with haustration in multiple colonic sites by ultrasonography 1. When taking Dioclear, it's crucial to maintain consistent levels in your bloodstream, and taking it at the same time each day is recommended. Do not crush, chew, or break the tablets unless specifically instructed to do so by your doctor. If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose rather than taking a double dose. Complete the full course of medication even if you feel better before it's finished. Dioclear works by targeting specific mechanisms in your body related to your condition, and maintaining consistent levels of the medication is crucial for its effectiveness. Always store Dioclear at room temperature away from moisture and heat, and keep it out of reach of children. It's also important to note that package inserts should provide clear and quantifiable dosage instructions, as emphasized in a study on inappropriate dosage instructions in package inserts 3. Furthermore, a low-volume bowel preparation regimen can be effective and improve patient tolerance, as shown in a study on the evaluation of a 1-day bowel preparation regimen with polyethylene glycol 3350 in children 4. Overall, proper timing and administration of bowel preparation agents, as well as clear dosage instructions, are essential for effective treatment with Dioclear.