What is the cause of eyelid popping?

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From the Research

Causes of Eyelid Popping

The causes of eyelid popping, also known as floppy eyelid syndrome, are numerous and can be challenging to diagnose. Some of the possible causes include:

  • Eyelid hyperlaxity with reactive palpebral conjunctivitis 1
  • Decreased amount of elastin within the tarsus, leading to laxity of the lid 2
  • Associations with ocular and systemic diseases, such as keratoconus, obstructive sleep apnea, obesity, and glaucoma 1, 3, 4
  • Genetic predispositions 4

Pathogenesis

The underlying pathogenesis of floppy eyelid syndrome remains elusive, although progress has been made in the identification of extracellular matrix changes in the tarsal plate 3. The condition is characterized by the abnormal laxity of the upper eyelids, often leading to chronic eye irritation and redness 4.

Clinical Features

The clinical features of floppy eyelid syndrome include:

  • Easily everted eyelids 1
  • Chronic papillary conjunctivitis in the upper eyelids 1
  • Nonspecific irritation, redness, or a foreign body sensation 2
  • Plait upper tarsus that is easily everted without excess manipulation 2

References

Research

Floppy eyelid syndrome: A comprehensive review.

The ocular surface, 2020

Research

Floppy eyelid syndrome: a diagnostic dilemma.

Journal of the American Optometric Association, 1999

Research

Floppy eyelid syndrome: stretching the limits.

Survey of ophthalmology, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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