What are the dose and duration of olanzapine and baclofen for intractable hiccups management?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 8, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

There are no official guidelines to assist in answering this question. I will search for relevant research papers instead.

The FDA Drug Labels for olanzapine (PO), baclofen (PO) do not address this question.

From the Research

Dose and Duration of Olanzapine and Baclofen

  • The dose and duration of olanzapine and baclofen for intractable hiccups management are not explicitly stated in the provided studies, except for a case report where a combination of baclofen and low-dose olanzapine therapy was used to control intractable hiccups 1.
  • Baclofen has been studied in a double-blind, randomized, controlled, cross-over study for the treatment of intractable hiccup, but the dose and duration are not specified in the provided text 2.
  • A systematic review of pharmacologic interventions for intractable and persistent hiccups mentions baclofen as one of the treatment options, but does not provide specific dose and duration information 3.
  • Another review of the management of intractable hiccups mentions baclofen as a potential first-line therapy, but also does not provide specific dose and duration information 4.
  • A review of the literature on intractable hiccups mentions that treatment is often based on experience and anecdotal evidence, and that there are no formal guidelines for the treatment of intractable hiccups, including dose and duration of medications like olanzapine and baclofen 5.

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.