From the FDA Drug Label
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman.
The use of Lotrisone (clotrimazole and betamethasone) during breastfeeding is not entirely clear, but caution is advised. There is limited information on the systemic absorption of topical corticosteroids and their presence in breast milk. However, systemically administered corticosteroids are secreted into breast milk in quantities that are not likely to have a deleterious effect on the infant. Considering this, it is recommended to exercise caution when using Lotrisone during breastfeeding, but the available data does not provide a clear answer to the question of safety 1.
From the Research
Lotrisone (clotrimazole and betamethasone) should be used with caution during breastfeeding, as the betamethasone component may be absorbed through the skin and potentially enter breast milk in small amounts. While clotrimazole is considered safe during breastfeeding as minimal amounts are absorbed systemically, the presence of betamethasone, a potent corticosteroid, raises concerns 2. If Lotrisone must be used while breastfeeding, it is recommended to apply it sparingly to the affected area, avoid applying it on or near the breasts, and thoroughly wash your hands after application to prevent accidental transfer to the infant. Additionally, do not cover the treated area with occlusive dressings as this increases absorption. The medication should be used for the shortest duration possible as directed by your healthcare provider. Some key considerations for breastfeeding mothers using Lotrisone include:
- Applying the medication sparingly to minimize exposure
- Avoiding application on or near the breasts
- Washing hands thoroughly after application
- Avoiding occlusive dressings
- Using the medication for the shortest duration possible Alternative antifungal treatments without corticosteroids, such as clotrimazole alone, may be preferable for breastfeeding mothers when appropriate for the condition being treated 3. It is essential to inform your healthcare provider that you are breastfeeding before using this medication, as they can provide personalized guidance and recommend the best course of treatment.