From the Research
The recommended dose of Caduet (amlodipine and atorvastatin) is typically 5 mg amlodipine/10 mg atorvastatin or 5 mg amlodipine/20 mg atorvastatin taken once daily, with dosage adjustments made according to individual response and tolerance, as supported by the most recent study 1. The dosage may be adjusted, with amlodipine ranging from 2.5-10 mg and atorvastatin from 10-80 mg daily. Key considerations for dosing include:
- Patient's specific condition
- Individual response and tolerance
- Potential interactions with other medications, such as CYP3A4 inhibitors
- Presence of hepatic impairment or elderly patients, who may require lower starting doses Caduet should be taken at the same time each day, with or without food. The medication combines a calcium channel blocker (amlodipine) to lower blood pressure by relaxing blood vessels and a statin (atorvastatin) to reduce cholesterol production in the liver, as described in 2, 3, 4, 5. Dose adjustments should only be made under medical supervision, and patients should report any muscle pain, weakness, or other side effects to their healthcare provider immediately, as noted in 1.