From the Research
Finasteride (PROSCAR) 5 mg tablet is not recommended for female pattern hair loss due to its potential teratogenic effects and limited evidence of efficacy in women. The most recent and highest quality study, a network meta-analysis published in 2024 1, found that 5 mg/day finasteride for 24 weeks had a high surface under the cumulative ranking curve (SUCRA) value, indicating its potential efficacy in treating female pattern hair loss. However, this study also highlighted the importance of considering the potential risks and benefits of finasteride treatment in women.
When considering finasteride treatment for female pattern hair loss, it is essential to weigh the potential benefits against the risks, particularly the risk of teratogenicity. A study published in 2019 2 found that a topical combination of 0.25% finasteride and 3% minoxidil was effective in increasing hair diameter in postmenopausal women with female pattern hair loss. However, this study also noted that finasteride should be reserved for postmenopausal women due to the risk of percutaneous absorption.
In terms of dosing, the 2024 network meta-analysis study 1 found that 5 mg/day finasteride for 24 weeks was a potentially effective regimen for treating female pattern hair loss. However, it is crucial to note that finasteride is not FDA-approved for female pattern hair loss, and its use in women is considered off-label.
Some key points to consider when evaluating finasteride treatment for female pattern hair loss include:
- Potential teratogenic effects: Finasteride is contraindicated in women who are or may become pregnant due to the risk of causing abnormalities in male fetal development.
- Limited evidence of efficacy: While some studies suggest that finasteride may be effective in treating female pattern hair loss, the evidence is limited, and more research is needed to fully understand its effects in women.
- Alternative treatments: FDA-approved treatments for female pattern hair loss include topical minoxidil 2% or 5% applied twice daily, or low-level laser therapy devices. Some dermatologists may also prescribe spironolactone or oral minoxidil off-label for women with hair loss.
Ultimately, women experiencing hair loss should consult with a dermatologist for proper diagnosis and treatment recommendations tailored to their specific condition. The dermatologist can help weigh the potential benefits and risks of finasteride treatment and determine the most effective treatment plan.