Differential Diagnosis for Sore Throat with Swollen Uvula without Fever
Single Most Likely Diagnosis
- Allergic Reaction: This is often the most common cause of a sore throat with a swollen uvula in the absence of fever. Allergies can cause localized swelling and irritation, leading to these symptoms.
Other Likely Diagnoses
- Irritant Exposure: Exposure to irritants such as smoke, pollution, or chemical fumes can cause throat irritation and swelling of the uvula.
- Gastroesophageal Reflux Disease (GERD): Stomach acid reflux can irritate the throat, leading to soreness and swelling of the uvula.
- Mild Trauma: Minor injuries to the throat, such as from shouting or a minor accident, can cause swelling and soreness.
Do Not Miss Diagnoses
- Angioedema: A potentially life-threatening condition that can cause rapid swelling of the uvula and throat, leading to airway obstruction. It often presents without fever and can be triggered by allergies or other factors.
- Epiglottitis: Although less common without fever, epiglottitis is a serious condition that can cause throat swelling and potentially lead to airway obstruction.
Rare Diagnoses
- Tumor or Cyst: Rarely, a tumor or cyst in the throat can cause swelling and soreness of the uvula.
- Infectious Mononucleosis (Mono): Although typically associated with fever, some cases of mono can present with sore throat and swollen uvula without fever, especially in the early stages.
- Behçet's Disease: A rare condition that can cause oral and genital ulcers, as well as other symptoms including throat swelling and soreness.