What is the best eye drop for a scratched cornea?

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Last updated: June 30, 2025View editorial policy

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From the Guidelines

For a scratched cornea, Cenegermin 20 μg/ml eye drops, used 6 times daily for 8 weeks, have shown the highest rates of corneal healing compared to other agents 1. When considering treatment for a scratched cornea, it's essential to prioritize healing and minimize the risk of complications.

  • The use of Cenegermin, as mentioned, has demonstrated significant benefits in promoting corneal healing 1.
  • Additionally, lubricating artificial tears can be used to provide comfort and support the healing process, applied every 2-4 hours as needed.
  • It's also important to note that while other agents like substance P, insulin-like growth factor-1, fibronectin, and thymosin beta 4 have shown some benefit, they remain investigational and should be considered under the guidance of a healthcare professional 1.
  • Topical corticosteroids may be used to reduce inflammation but should be monitored closely due to potential side effects like increased intraocular pressure and cataract formation 1.
  • The application of amniotic membranes or tissue adhesives may be considered in more severe cases, but these should only be applied by a qualified healthcare professional 1.
  • It's crucial to seek medical attention for a scratched cornea to determine the best course of treatment and to monitor for any signs of complications, such as worsening pain, decreased vision, or increased redness.

From the Research

Best Eye Drops for Scratched Cornea

  • The best eye drops for a scratched cornea may include those with nonsteroidal anti-inflammatory drugs (NSAIDs) such as ketorolac tromethamine 0.5% ophthalmic solution, as they have been shown to decrease pain, photophobia, and foreign body sensation in patients with corneal abrasions 2, 3.
  • Topical artificial tears and rewetting drops can also be used to treat corneal abrasions and are generally safe and effective, especially if they are preservative-free 4.
  • The use of antibiotic drops such as tobramycin in combination with NSAID drops and a therapeutic contact lens may also be an effective treatment for traumatic corneal abrasions 5.
  • However, it is essential to note that some topical medications, including moxifloxacin, can cause corneal deposits as a side effect, and preservative-free options should be considered to minimize the risk of eye irritation 6.

Key Considerations

  • The choice of eye drops for a scratched cornea should be based on the individual patient's needs and the severity of the abrasion.
  • Patients should consult with an ophthalmologist to determine the best course of treatment for their specific condition.
  • It is crucial to follow the recommended dosage and administration instructions for any prescribed eye drops to ensure safe and effective use.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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