From the Guidelines
Night sweats and excessive thirst are not typically listed as common withdrawal symptoms when stopping Vraylar (cariprazine). If you're experiencing these symptoms after discontinuing Vraylar, they may be unrelated to the medication discontinuation or could potentially represent underlying conditions that were being masked while on the medication. Vraylar is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, and its common withdrawal effects include insomnia, anxiety, restlessness, and sometimes rebound symptoms of the original condition. When stopping Vraylar, it's generally recommended to taper gradually under medical supervision rather than stopping abruptly to minimize withdrawal effects.
Some studies have reported various withdrawal symptoms from other medications, such as diarrhea, dizziness, dry mouth, fatigue, headache, sexual dysfunction, sweating, tremor, and weight gain 1. However, these symptoms are not specific to Vraylar and may not be directly related to its withdrawal.
Night sweats and excessive thirst could potentially indicate other medical issues such as blood sugar abnormalities, hormonal changes, infections, or other medication effects. These symptoms warrant medical evaluation, especially if they persist or are severe. Contact your healthcare provider about these symptoms, as they can determine whether they're related to Vraylar discontinuation or if further investigation is needed for another cause.
In general, when managing withdrawal symptoms or potential side effects from any medication, including Vraylar, it's crucial to follow the guidance of a healthcare provider to ensure safe and effective management of the condition being treated, as well as any side effects that may arise. This may involve adjusting the dosage, switching to a different medication, or addressing underlying conditions that could be contributing to the symptoms experienced.
Given the potential for various symptoms and the importance of individualized care, consulting a healthcare provider is essential for anyone experiencing night sweats and excessive thirst after stopping Vraylar, to receive a proper evaluation and guidance tailored to their specific situation.
From the Research
Night Sweats and Excessive Thirst After Stopping Vraylar (Cariprazine)
- Night sweats can be a symptom of various conditions, including mood disorders, and can be caused by certain medications, such as antidepressants and antipsychotics 2, 3.
- Stopping a medication like Vraylar (cariprazine) may lead to withdrawal symptoms, but there is limited research on the specific symptoms of night sweats and excessive thirst after discontinuation.
- A study on aripiprazole, a medication similar to cariprazine, found that two patients developed hyperhidrosis (excessive sweating) while taking the medication, which resolved after discontinuation 4.
- Excessive sweating has been associated with antidepressants, including selective serotonin-reuptake inhibitors (SSRIs) and venlafaxine, and can be managed with dose reduction, substitution, or addition of an agent to control sweating 3, 5.
- The sudden onset of night sweats and excessive thirst after stopping Vraylar (cariprazine) may be related to the discontinuation of the medication, but further evaluation is needed to determine the underlying cause 6, 2.
Possible Causes of Night Sweats and Excessive Thirst
- Mood disorders, such as depression or anxiety, which can be related to the use of Vraylar (cariprazine) 6.
- Withdrawal symptoms from stopping Vraylar (cariprazine), although this is not well-documented in the literature.
- Other medical conditions, such as hyperthyroidism, gastroesophageal reflux disease, or obesity, which can cause night sweats and excessive thirst 6, 2.
- Medication-induced sweating, which can occur with certain antidepressants and antipsychotics 4, 3, 5.