From the Research
Management of a calcified vas deferens typically involves observation without specific intervention as it is generally asymptomatic and benign. If the calcification is discovered incidentally on imaging, no treatment is usually necessary 1. When symptoms occur, such as pain or discomfort, initial management includes non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (400-600mg three times daily) or naproxen (500mg twice daily) for pain relief. In cases where fertility is desired and the calcification contributes to obstruction, surgical intervention may be considered, including vasovasostomy (reconnection of the vas deferens) or sperm retrieval techniques such as testicular sperm extraction (TESE) combined with in vitro fertilization.
Key Considerations
- The condition is more common in men with a history of genitourinary infections or trauma and is sometimes associated with diabetes or other systemic conditions that promote tissue calcification 2, 3.
- Calcification of the vas deferens often results from previous inflammation or infection, such as epididymitis or vasitis, and represents calcium deposition in the wall of the vas deferens.
- The most recent study 1 highlights the importance of considering underlying conditions such as diabetes and chronic kidney disease in the management of calcified vas deferens.
Treatment Approach
- Observation without intervention for asymptomatic cases
- NSAIDs for pain relief in symptomatic cases
- Surgical intervention for obstructive cases affecting fertility It is essential to note that the management approach should be individualized based on the patient's specific condition and underlying causes, as emphasized in the review of literature 4.