What are the benefits and dangers of AID-9604 (Acute Insulin-like Drug 9604)?

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Last updated: June 30, 2025View editorial policy

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From the Guidelines

AID-9604 is not recommended for use due to its experimental nature and lack of regulatory approval, as its safety profile has not been adequately established through proper clinical trials. The benefits of AID-9604, also known as AOD-9604 or hGH fragment 177-191, are largely theoretical and include potential fat reduction, improvement in metabolism, and assistance with weight loss resistant to other methods 1. However, the dangers of AID-9604 are substantial and include unknown long-term effects, potential hormonal disruptions, risk of contaminated products when purchased from unregulated sources, possible cardiovascular effects, and unpredictable interactions with other medications.

Key Considerations

  • The peptide is not FDA-approved for human use and should not be used without medical supervision.
  • The benefits of AID-9604 remain largely theoretical and lack robust clinical evidence.
  • The dangers of AID-9604 are substantial and include unknown long-term effects, potential hormonal disruptions, and risk of contaminated products.
  • The peptide works by supposedly mimicking the fat-reducing effects of human growth hormone without its growth-promoting properties, targeting fat metabolism specifically.

Recommendations

  • Due to its experimental nature and lack of regulatory approval, I strongly advise against self-administration of AID-9604.
  • Patients should be educated on the potential risks and benefits of AID-9604 and the importance of medical supervision.
  • Further research is needed to establish the safety and efficacy of AID-9604 for human use.

Conclusion is not allowed, so the answer will be ended here.

From the Research

Benefits of AID-9604

  • AID-9604, also known as AOD-9604, is a peptide that mimics the lipolytic properties of growth hormone without the diabetogenic side effects 2
  • It is being developed for the potential treatment of obesity, with phase IIa trials underway by 2002 3

Dangers of AID-9604

  • AOD-9604 is banned by the World Anti-doping Agency (WADA) as it may be used as a performance-enhancing drug 2
  • The peptide is available on several Internet websites and has been identified in confiscated vials in the USA, highlighting the potential for abuse 2
  • There is a lack of high-quality, directly comparative evidence on the treatment's impact on patient-relevant outcomes, including potential harms 4

Metabolism and Detection

  • AOD-9604 is a peptide consisting of the C-terminal fragment of human growth hormone from amino acids 177-191 with an additional tyrosine residue at the N-terminus of the peptide 2
  • A solid-phase extraction method has been validated to detect AOD-9604 in urine, with a limit of detection of 50 pg/mL 2
  • Six potential metabolites of the peptide have been identified, with one metabolite being significantly more stable than the others or the parent compound 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Detection and in vitro metabolism of AOD9604.

Drug testing and analysis, 2015

Research

AOD-9604 Metabolic.

Current opinion in investigational drugs (London, England : 2000), 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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