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Last updated: July 1, 2025View editorial policy

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Differential Diagnosis for Dental Pain

Dental pain can be caused by various conditions, and a thorough differential diagnosis is essential for accurate diagnosis and treatment. The following categories outline the possible causes of dental pain:

  • Single Most Likely Diagnosis
    • Dental caries (tooth decay): This is the most common cause of dental pain, resulting from bacterial infection and acid production that damages tooth enamel and dentin.
  • Other Likely Diagnoses
    • Pulpitis: Inflammation of the dental pulp, often caused by deep caries, trauma, or infection, leading to pain and sensitivity.
    • Gingivitis or periodontitis: Inflammation of the gums (gingivitis) or supporting structures of the teeth (periodontitis), which can cause pain, swelling, and bleeding.
    • Dental abscess: A localized collection of pus in the tissues surrounding the teeth, often caused by bacterial infection, leading to severe pain and swelling.
    • Cracked tooth syndrome: A condition where a tooth is cracked, causing pain and sensitivity, often when chewing or biting.
  • Do Not Miss Diagnoses
    • Acute apical periodontitis: A condition where the tissues surrounding the root of the tooth become inflamed, causing severe pain and potentially leading to more serious complications if left untreated.
    • Dental trauma: Trauma to the teeth or surrounding tissues, which can cause pain, swelling, and potentially lead to more serious complications, such as tooth avulsion or fracture.
    • Trigeminal neuralgia: A condition characterized by sudden, severe facial pain, often triggered by stimulation of the trigeminal nerve, which can be mistaken for dental pain.
    • Sinusitis: Inflammation of the sinuses, which can cause referred pain to the teeth and face, often mistaken for dental pain.
  • Rare Diagnoses
    • Odontogenic tumors: Rare, benign or malignant tumors that originate in the teeth or surrounding tissues, which can cause pain, swelling, and other symptoms.
    • Eruption cyst: A rare condition where a cyst forms over an erupting tooth, causing pain, swelling, and discomfort.
    • Dentinogenesis imperfecta: A rare genetic disorder that affects the development of tooth dentin, causing discoloration, sensitivity, and pain.
    • Eagle syndrome: A rare condition where the styloid process or ligaments become elongated or inflamed, causing pain and discomfort in the face, throat, and teeth.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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