How is lip ptosis after Botox (Botulinum toxin) treated?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 1, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Lip ptosis after Botox is typically treated with a combination of time, supportive measures, and in some cases, additional interventions, with the primary treatment being patience as Botox effects are temporary and will naturally resolve within 3-4 months. The treatment approach for lip ptosis after Botox involves several strategies to manage the condition effectively.

  • Time: Allowing the natural resolution of Botox effects, which typically occurs within 3-4 months as the neuromuscular blockade wears off 1.
  • Supportive measures: Patients can use physical support techniques such as lip taping or manual exercises where they practice lifting the affected lip several times daily.
  • Additional interventions: For severe cases that significantly impact quality of life, a small amount (1-2 units) of Botox can be strategically injected into opposing muscles to create balance, though this requires expert administration, as seen in a case where botulinum toxin was used to treat full eyelid ptosis following Botox injection 1.
  • Medications: Low-dose oral anticholinesterase medications like pyridostigmine (30-60mg three times daily) might temporarily improve function by increasing acetylcholine availability at the neuromuscular junction, but this should only be used under medical supervision. These treatments work because Botox causes ptosis by blocking acetylcholine release at nerve terminals, preventing muscle contraction, and interventions either support the affected area until natural recovery occurs or attempt to counterbalance the effect. It's essential to note that while treatments with botulinum toxin A are considered safe, unexpected results can occur, as reported in a case of smile asymmetry and excessive lowering of the lower lip after botulinum toxin A application in the lower third of the face 2. In such cases, correction can be made with a new injection of botulinum toxin A in the hyperactive muscle, highlighting the importance of expert administration and careful consideration of anatomical complexities when using Botox for cosmetic purposes 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.