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Differential Diagnosis for Rounded Density at Left Vesicoureteric Junction

  • Single most likely diagnosis
    • Vesicoureteric Stone: This is the most likely diagnosis given the location at the vesicoureteric junction and the description of a rounded density. Stones at this location can cause obstruction and are a common indication for ureteroscopic lithotripsy.
  • Other Likely diagnoses
    • Phlebolith: As mentioned, a phlebolith could present similarly on imaging. However, phleboliths are typically smaller and less likely to cause significant obstruction compared to a stone. They are a consideration but less likely given the size (5.5 mm) and the clinical context suggesting a need for intervention like ureteroscopic lithotripsy.
    • Blood clot: A blood clot could potentially present as a rounded density, especially if it has formed in the context of a stone causing ureteral trauma or in the setting of another ureteral pathology. However, the size and the specific location at the vesicoureteric junction make this less likely than a stone.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Malignancy (e.g., transitional cell carcinoma): Although less common, a tumor at the vesicoureteric junction could present as a rounded density. Missing a diagnosis of malignancy could have severe consequences, making it crucial to consider, especially if there are atypical features or if the patient does not respond as expected to treatment for a stone.
    • Inflammatory or infectious lesions: Certain infections or inflammatory conditions could potentially cause a mass-like lesion at the vesicoureteric junction, though these would be less common and might be accompanied by other symptoms such as fever, pain, or changes in urination.
  • Rare diagnoses
    • Metastatic disease: Rarely, metastatic disease from another primary cancer could present as a mass at the vesicoureteric junction. This would be an uncommon presentation for metastatic disease but should be considered in patients with a known history of cancer.
    • Vascular anomalies: Certain vascular anomalies, such as an arteriovenous malformation, could potentially present as a rounded density, though this would be exceedingly rare and likely accompanied by other clinical findings.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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