From the Guidelines
A Glomerular Filtration Rate (GFR) of 46 mL/min/1.73m² corresponds to Stage 3A Chronic Kidney Disease (CKD). This stage represents moderate kidney damage with reduced kidney function. CKD is classified into five stages based on GFR values, with Stage 3 being further divided into 3A (GFR 45-59) and 3B (GFR 30-44) 1. With a GFR of 46, you fall into Stage 3A, as it is above the threshold of 45 mL/min/1.73m².
Key Considerations
- At this stage, regular monitoring by a nephrologist is recommended, typically every 3-6 months.
- You should have your blood pressure, blood glucose, and urine protein levels checked regularly.
- Medications that may be prescribed include ACE inhibitors or ARBs to control blood pressure and reduce protein in urine.
- Dietary modifications are also important, including limiting sodium, potassium, and phosphorus intake. The kidneys are struggling to filter waste products efficiently at this stage, which is why the GFR is reduced to less than half of normal kidney function (normal being above 90 mL/min/1.73m²) 1. Taking steps now to manage blood pressure, control diabetes if present, and follow medical advice can help slow progression to more advanced stages of kidney disease.
Management and Prevention
- Regular monitoring and management can help prevent the progression of CKD to more advanced stages.
- Lifestyle modifications, such as a healthy diet and regular exercise, can also help slow disease progression.
- It is essential to work closely with a healthcare provider to develop a personalized treatment plan.
From the Research
CKD Stage Classification
The Chronic Kidney Disease (CKD) stage for a Glomerular Filtration Rate (GFR) of 46 can be determined based on the classification system provided by Kidney Disease: Improving Global Outcomes (KDIGO) 2. According to this system, CKD is classified into five stages based on the level of GFR.
GFR Ranges for CKD Stages
The GFR ranges for each CKD stage are as follows:
- Stage 1: GFR ≥ 90 mL/min/1.73 m²
- Stage 2: GFR = 60-89 mL/min/1.73 m²
- Stage 3: GFR = 30-59 mL/min/1.73 m², which can be further subdivided into:
- Stage 3A: GFR = 45-59 mL/min/1.73 m²
- Stage 3B: GFR = 30-44 mL/min/1.73 m²
CKD Stage for GFR 46
Based on the above classification, a GFR of 46 falls into the category of Stage 3B CKD, as it is between 30-44 mL/min/1.73 m² is not correct, it is between 45-59 mL/min/1.73 m², so it is Stage 3A 3.