From the Guidelines
Erythema nodosum can occur on the arms, although it is more commonly found on the extensor surfaces of the lower legs, particularly the anterior tibial areas. According to the study by 1, erythema nodosum is characterized by raised, tender, red or violet subcutaneous nodules of 1–5 cm in diameter, and it commonly affects the extensor surfaces of the extremities. While the study does not specifically mention the arms as a common location, it does state that the condition can affect the extremities, which includes the arms.
The condition represents a delayed hypersensitivity reaction and is often triggered by infections, medications, inflammatory bowel disease, sarcoidosis, or pregnancy. Treatment focuses on addressing the underlying cause while managing symptoms with NSAIDs, rest, and elevation of affected limbs. In more severe cases, potassium iodide, colchicine, or systemic corticosteroids might be prescribed.
It is essential to note that the study by 1 provides the most relevant information on erythema nodosum, and its findings should be prioritized when making a diagnosis or developing a treatment plan. The study by 1 provides information on the treatment of skin and soft tissue infections, but it is not directly relevant to the diagnosis or treatment of erythema nodosum.
Key points to consider when diagnosing or treating erythema nodosum include:
- The condition is characterized by tender, red or violet, raised nodules
- It commonly affects the extensor surfaces of the lower legs, but can also occur on the arms and other parts of the body
- Treatment focuses on addressing the underlying cause and managing symptoms
- NSAIDs, rest, and elevation of affected limbs are commonly used to manage symptoms
- Systemic corticosteroids may be prescribed in more severe cases.
From the Research
Erythema Nodosum Location
- Erythema nodosum is typically characterized by tender, erythematous, subcutaneous nodules located on the lower extremities, particularly on the anterior surface of the legs, shins, ankles, and knees 2, 3, 4, 5.
- The condition is known to occur mainly on the pretibial area of the lower limbs 4.
- While the provided studies primarily discuss the occurrence of erythema nodosum on the lower extremities, there is no explicit mention of the condition occurring on the arms in the given evidence 2, 3, 4, 5, 6.
Clinical Variants and Diagnosis
- Erythema nodosum can be associated with various systemic diseases, infections, and drug therapies, or it may be idiopathic 2, 3, 4, 5, 6.
- The diagnosis of erythema nodosum involves a comprehensive history, physical examination, laboratory tests, and sometimes a biopsy to rule out underlying conditions 3, 4, 5, 6.