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Differential Diagnosis for Palpitations

The patient's symptoms of palpitations, chest tightness, lightheadedness, and anxiety, which resolved spontaneously, suggest a cardiac or anxiety-related etiology. The following differential diagnoses are considered:

  • Single most likely diagnosis
    • Panic Attack: The patient's symptoms of palpitations, chest tightness, lightheadedness, and anxiety are classic for a panic attack. The fact that her symptoms resolved spontaneously and she had a similar episode in the past further supports this diagnosis.
  • Other Likely diagnoses
    • Supraventricular Tachycardia (SVT): Although the patient's EKG was normal, SVT can cause palpitations and chest tightness. The fact that her symptoms resolved spontaneously is consistent with SVT.
    • Anxiety Disorder: The patient's symptoms of anxiety and panic attacks suggest an underlying anxiety disorder.
    • Mitral Valve Prolapse: This condition can cause palpitations, chest tightness, and anxiety, especially in young women.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cardiac Arrhythmias (e.g., Ventricular Tachycardia): Although unlikely, cardiac arrhythmias can be life-threatening and must be considered in the differential diagnosis.
    • Pulmonary Embolism: Although the patient's symptoms do not strongly suggest pulmonary embolism, it is a potentially life-threatening condition that must be considered.
    • Hypertrophic Cardiomyopathy: This condition can cause palpitations, chest tightness, and sudden death, especially in young athletes.
  • Rare diagnoses
    • Pheochromocytoma: This rare tumor can cause episodic palpitations, chest tightness, and anxiety due to catecholamine release.
    • Thyroid Storm: Although rare, thyroid storm can cause palpitations, chest tightness, and anxiety, especially in patients with a history of thyroid disease.
    • Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT): This rare genetic disorder can cause palpitations, chest tightness, and sudden death, especially in young patients.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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