From the Guidelines
The treatment for alpha-streptococcus in urine should involve a 7-14 day regimen of antibiotics, with a preference for discontinuing the use of urinary catheters as soon as possible. When considering the treatment for alpha-streptococcus in urine, it's crucial to prioritize the most recent and highest quality evidence available. According to the 2009 international clinical practice guidelines from the Infectious Diseases Society of America 1, the use of antibiotics such as levofloxacin (750 mg intravenously or orally once daily for 5 days) or ciprofloxacin (400 mg intravenously and/or ciprofloxacin 500 mg orally twice daily for 10 days) may be effective in treating urinary tract infections (UTIs). Some key points to consider in the treatment of alpha-streptococcus in urine include:
- Discontinuing the use of urinary catheters as soon as possible to prevent further complications 1
- Using a 7-14 day regimen of antibiotics for most patients with catheter-associated UTIs (CA-UTIs) 1
- Considering a 5-day regimen with levofloxacin for patients with mild CA-UTIs 1
- Avoiding the use of moxifloxacin due to uncertainty regarding effective concentrations in urine 1
- Adjusting regimens based on culture and susceptibility results, as well as the clinical course of the patient 1 It's essential to note that alpha-streptococcus is less commonly associated with UTIs than other bacteria, so additional testing may be necessary to confirm the diagnosis and determine antibiotic sensitivity. Completing the full course of antibiotics and increasing fluid intake can help manage the infection and prevent further complications.
From the FDA Drug Label
Genitourinary tract infections, including acute prostatitis, caused by Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae The FDA drug label does not answer the question.
From the Research
Treatment for Alpha-Streptococcus in Urine
The treatment for alpha-streptococcus (alpha strep) in urine, indicating a possible urinary tract infection (UTI), can be approached with various antibiotics.
- The choice of antibiotic depends on the sensitivity of the bacteria and the severity of the infection.
- Studies have shown that antibiotics such as cephalexin 2, amoxicillin-clavulanic acid 3, 4, 5, and trimethoprim-sulphamethoxazole 6 can be effective in treating UTIs.
Antibiotic Options
- Cephalexin: This antibiotic has been shown to be effective in treating UTIs, with a cure rate of 94.7% after 10 days of treatment 2.
- Amoxicillin-clavulanic acid: This combination has been shown to be effective in treating UTIs caused by beta-lactamase-producing bacteria, with a cure rate of 63.6% to 77.7% 3, 4.
- Trimethoprim-sulphamethoxazole: This combination has been shown to be effective in treating UTIs caused by Streptococcus faecalis, but its use for more than two weeks can lead to the development of resistance 6.
High-Dose Amoxicillin with Clavulanic Acid
- A recent study has shown that high-dose amoxicillin with clavulanic acid can be effective in treating UTIs caused by extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae, with no therapeutic failures or recurrences observed in the study group 5.
- This treatment option may be considered for patients with recurrent UTIs caused by ESBL-producing bacteria.