What are the DiSe (Disease Severity) criteria compared to VOTE (Vascular Occlusion Treatment Evaluation) for managing certain medical conditions?

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Last updated: July 2, 2025View editorial policy

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From the Guidelines

The DiSe criteria are not explicitly defined in the provided evidence, and therefore, cannot be directly compared to the VOTE criteria. However, based on the context of managing retinal vascular diseases, particularly diabetic retinopathy and retinal vein occlusions, it is essential to assess the severity of the disease and monitor treatment response. The provided evidence focuses on different aspects of disease management, including patient outcome criteria, medical history, ocular exams, and retinal imaging 1. In the context of diabetic foot infections, various classification systems are used, such as PEDIS, IDSA, UT, and S(AD)SAD, which help predict outcomes and guide treatment decisions 1. Similarly, in coronary artery bypass graft surgery, guidelines recommend using specific criteria, such as the SYNTAX score, to determine the best course of treatment 1. When managing retinal vascular diseases, ophthalmologists typically use anti-VEGF medications, and the treatment approach may involve initial monthly injections followed by treatment intervals determined by disease activity. Key factors in managing these conditions include:

  • Assessing the overall severity of retinal disease
  • Monitoring treatment response
  • Determining treatment urgency and follow-up intervals
  • Using complementary systems to make precise decisions about treatment and monitoring. Given the lack of explicit information on the DiSe criteria, it is crucial to rely on the most recent and highest-quality evidence available, which may involve using established classification systems and guidelines to inform treatment decisions 1.

From the Research

DiSe Criteria vs VOTE

There are no research papers provided to directly compare the DiSe (Disease Severity) criteria to the VOTE (Vascular Occlusion Treatment Evaluation) for managing certain medical conditions.

Available Information

  • The provided studies focus on the treatment of lower respiratory tract infections with ceftriaxone 2, 3 and its use in pediatric hospitals 4.
  • Other studies discuss precision dosing priority criteria for drugs and disease variables 5 and the value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis 6.
  • Key points from these studies include:
    • Ceftriaxone is effective in treating lower respiratory tract infections 2, 3.
    • Ceftriaxone is often overused as empiric therapy in pediatric hospitals 4.
    • Precision dosing is important for optimizing drug effectiveness and minimizing toxicity 5.
    • Antibiotic levels in serum and infected tissues can predict antibacterial efficacy 6.

Limitations

  • The provided studies do not directly address the DiSe criteria or VOTE.
  • There is no information available to compare or contrast these two criteria.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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