Differential Diagnosis
- Single most likely diagnosis
- Osteomalacia: This condition is characterized by the softening of bones due to a deficiency of vitamin D and calcium. The patient's symptoms of generalized bone pain, muscle weakness, and generalized demineralization of bones are consistent with osteomalacia. The absence of the lamina dura and fracture-like lines in the bones of the feet also support this diagnosis. The frequent episodes of loose bulky stools may indicate malabsorption, which could contribute to the development of osteomalacia.
- Other Likely diagnoses
- Celiac disease: This condition can cause malabsorption of nutrients, including vitamin D and calcium, leading to bone demineralization and osteomalacia. The patient's symptoms of loose bulky stools and abdominal distension are consistent with celiac disease.
- Crohn's disease: Similar to celiac disease, Crohn's disease can cause malabsorption of nutrients, leading to bone demineralization and osteomalacia. The patient's symptoms of loose bulky stools and abdominal distension are also consistent with Crohn's disease.
- Do Not Miss
- Hyperparathyroidism: This condition can cause bone resorption and demineralization, leading to symptoms similar to those experienced by the patient. Although less likely, hyperparathyroidism can have serious consequences if left untreated, making it a "do not miss" diagnosis.
- Multiple myeloma: This condition can cause bone pain, muscle weakness, and bone demineralization. Although rare in a 25-year-old, multiple myeloma can have serious consequences if left untreated, making it a "do not miss" diagnosis.
- Rare diagnoses
- Fibrous dysplasia: This condition can cause bone pain, muscle weakness, and bone demineralization. However, it is a rare condition and would be less likely in this patient.
- Hypophosphatasia: This condition is a rare genetic disorder that can cause bone pain, muscle weakness, and bone demineralization. However, it is a rare condition and would be less likely in this patient.