What is the recommended treatment for milia involving the eyelid?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 3, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

The recommended treatment for milia involving the eyelid is gentle extraction performed by a dermatologist or ophthalmologist, or alternatively, treatment with a CO2 fractional laser as reported in a case study 1. This approach prioritizes minimizing the risk of eye injury and promoting effective removal of the milia. The procedure involves making a tiny incision in the cyst with a sterile needle or blade, followed by careful expression of the keratin contents. Prior to extraction, the area may be cleaned with an antiseptic solution and local anesthesia might be used for comfort. For persistent or numerous milia, topical retinoids like tretinoin 0.025-0.05% cream may be prescribed for nightly application, avoiding direct contact with the eye. Some key points to consider in the treatment of milia involving the eyelid include:

  • Avoiding self-extraction or picking at the milia to prevent infection, scarring, or eye damage
  • Using warm compresses applied to the area for 5-10 minutes daily to help soften the milia before professional extraction
  • Considering alternative treatments such as chemical peels containing salicylic acid or glycolic acid at low concentrations for use away from the eye margin, as these can increase cell turnover and prevent keratin buildup that forms milia 2. However, the most recent and highest quality study specifically addressing milia en plaque of the eyelid suggests the use of a CO2 fractional laser as a potentially effective treatment option 1.

References

Research

Tretinoin peels versus glycolic acid peels in the treatment of Melasma in dark-skinned patients.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.