From the Research
Pristiq (desvenlafaxine) can cause increased thirst, and patients experiencing this side effect should discuss it with their healthcare provider to determine the best course of action, as it may be related to the medication's effect on fluid balance or dry mouth, as reported in studies such as 1.
Potential Causes of Increased Thirst
- Dry mouth: a common side effect of Pristiq that can contribute to the sensation of thirst
- Fluid balance: Pristiq can affect the body's fluid balance, leading to increased thirst
- Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): a rare but potential cause of hyponatremia and increased thirst, as reported in cases such as 2 and 3
Management of Increased Thirst
- Staying hydrated by drinking water throughout the day
- Discussing the symptom with a healthcare provider to determine the best course of action
- Considering sugar-free candies or gum to help with dry mouth symptoms
- Monitoring for severe or concerning symptoms such as excessive urination, dizziness, or confusion, and seeking medical attention promptly if they occur
Importance of Medical Supervision
- Never stopping Pristiq suddenly without medical supervision, as this can lead to withdrawal symptoms
- Working with a healthcare provider to manage side effects and adjust treatment as needed to minimize risks and optimize outcomes, as emphasized in studies such as 1 that highlight the importance of considering the tolerability profile of each antidepressant.