What are the contraindications for breastfeeding?

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Last updated: July 3, 2025View editorial policy

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From the Guidelines

Breastfeeding is contraindicated in mothers with HIV infection, human T-cell lymphotropic virus type I or II infection, untreated brucellosis, or suspected or confirmed Ebola virus disease, as well as in infants with classic galactosemia, as stated in the most recent guidelines from the American Academy of Pediatrics 1.

Contraindications to Breastfeeding

The following are contraindications to breastfeeding:

  • HIV infection in the mother
  • Human T-cell lymphotropic virus type I or II infection
  • Untreated brucellosis
  • Suspected or confirmed Ebola virus disease
  • Classic galactosemia in the infant

Medications and Breastfeeding

Most medications are compatible with breastfeeding, but certain medications, such as chemotherapy drugs, radioactive compounds, and drugs of abuse, are contraindicated 1.

Infectious Diseases and Breastfeeding

Mothers with certain infectious diseases, such as active untreated tuberculosis or active herpes simplex lesions on the breast, should avoid breastfeeding until properly treated 1.

Other Contraindications

Women who have undergone breast surgery that has severed milk ducts may have insufficient milk production, and breastfeeding may not be possible 1.

Benefits of Breastfeeding

Despite these contraindications, breastfeeding remains safe and beneficial for both mother and infant in most situations, including most common illnesses and medications, and has been shown to decrease the severity of neonatal withdrawal syndrome in infants born to women with opioid use disorder 1.

From the Research

Contraindications for Breastfeeding

The contraindications for breastfeeding are limited and primarily related to maternal illness, the need for certain medications, or rare infant conditions. Some of the key points to consider include:

  • Maternal illness: Certain maternal illnesses may necessitate the cessation of breastfeeding, although this is not common 2.
  • Medications: The use of medication by the nursing mother is a common reason for the cessation of breastfeeding, but few drugs have been demonstrated to be absolutely contraindicated during breastfeeding 3, 4.
  • Infant conditions: Rare infants with inborn errors of metabolism may have contraindications to breastfeeding 2.
  • Drug accumulation: Identifying situations with potential for drug accumulation in the breastfed infant is crucial when assessing the risk of breastfeeding while taking medication 5.

Assessment of Risks and Benefits

When considering the contraindications for breastfeeding, it is essential to assess the risks and benefits for both mother and child. This includes:

  • Pharmacokinetics: Understanding how drugs are transferred from the mother's blood to the milk and the potential impact on the infant 3, 4.
  • Risk to the infant: Evaluating the potential risk to the infant from exposure to drugs in the milk 5, 4.
  • Benefits of breastfeeding: Weighing the benefits of breastfeeding against the potential risks, including the benefits for maternal and infant health 6.
  • Maternal willingness: Considering the mother's willingness to breastfeed and her concerns about medication use 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Breast-feeding and infant health.

Seminars in perinatology, 1979

Research

Medication and breastfeeding.

Journal of biological regulators and homeostatic agents, 2012

Research

Drugs and breastfeeding: instructions for use.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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