What is the relationship between low testosterone and hematuria?

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Last updated: July 4, 2025View editorial policy

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From the Guidelines

Low testosterone is not directly linked to hematuria (blood in urine), and these conditions generally have different causes. Hematuria is typically caused by urinary tract infections, kidney stones, enlarged prostate, kidney disease, or bladder/kidney cancer. Low testosterone, on the other hand, results from aging, testicular injury, hormonal disorders, or certain medications. In rare cases where both conditions occur simultaneously, it's usually coincidental or related to a common underlying cause like prostate issues. For example, an enlarged prostate (which can occur in men with normal or low testosterone) may cause both urinary symptoms including hematuria and potentially affect testosterone production. If you experience hematuria, you should seek immediate medical attention regardless of testosterone status, as it requires proper evaluation to identify the cause. Treatment will depend on the specific diagnosis rather than testosterone levels. Blood work, urinalysis, and possibly imaging studies would be needed to determine the appropriate course of action, as suggested by studies such as 1. It's essential to note that while some studies, like 1, discuss the relationship between low testosterone and various health conditions, including cardiovascular disease, the direct link between low testosterone and hematuria is not established. Therefore, the primary focus should be on evaluating and treating the underlying cause of hematuria, rather than assuming a direct connection to testosterone levels.

From the Research

Relationship Between Low Testosterone and Hematuria

There is limited direct evidence on the relationship between low testosterone and hematuria. However, some studies provide insights into the potential connections between these two conditions:

  • Hematuria, or the presence of blood in the urine, can be a symptom of various underlying conditions, including urinary tract infections, kidney stones, and certain types of cancer 2, 3, 4.
  • Testicular cancer, which can cause hematuria, has been linked to low testosterone levels in some cases 3.
  • Low testosterone, or hypogonadism, is a condition that can be associated with various health issues, including metabolic syndrome and cardiovascular disease 5.
  • In patients with end-stage renal disease, low testosterone levels have been linked to increased risk of infection-related hospitalization and all-cause mortality 6.

Potential Connections

While there is no direct evidence on the relationship between low testosterone and hematuria, some potential connections can be inferred:

  • Testicular cancer, which can cause low testosterone, can also cause hematuria 3.
  • Certain underlying conditions, such as kidney disease, can cause both low testosterone and hematuria 6.
  • Hormonal imbalances, including low testosterone, can increase the risk of certain health issues, including infections and cardiovascular disease, which can also cause hematuria 5, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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